NOTCH1 Antibody (clone mN1A)

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Antibody:	Mouse Monoclonal
Applications:	Flow Cytometry, Immunohistochemistry (general), Immunohistochemistry, Frozen, Western Blot
Reactivity:	Mouse
Format:	Liquid

$296.00each

Catalog Number: LS-C44817-0.1

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Description: NOTCH1 antibody LS-C44817 is an unconjugated mouse monoclonal antibody to mouse NOTCH1. Validated for Flow, IHC and WB.
Application: FC, IHC, IHC-F, WB
Reactivity: Ms
Intended Use: Research Use Only
Guarantees: This antibody carries the LSBio 100% Guarantee. ✓
Category: Antibodies > Primary Antibodies > Monoclonal Antibodies
Alternative Names: Notch 1 | NOTCH1 | TAN1
Recommended Dilution: IHC-F: 1:50 - 1:200
UniProt Number: P46531
NCBI GenBank: NM_017617 | NP_060087.3
SwissProt: P46531

Target: Mouse NOTCH1
Antigen Species: Mouse
Epitope: Specific for mouse Notch1, a single transmembrane receptor which is expressed in a range of cells including hematopoietic cells in mouse fetal liver, adult thymus and bone marrow. Notch1 plays a role in embryonic development and tissue homeostasis in the adult. Recent work has suggested a further role for this receptor in the regulation of lymphopoiesis and myelopoiesis. Following ligand binding, Notch1 is cleaved in the transmembrane domain, releasing the Notch intracellular domain (NICD) to translocate to the nucleus, where it plays a role in the modulation of gene expression.
Gene Name: NOTCH1

Immunogen: Synthetic peptide corresponding to cdc10-NCR region within mouse Notch1
Immunogen Type: Synthetic Peptide (Linear)

Storage Conditions: Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.
Recommended Storage Buffer: PBS