NOD2 / CARD15 Antibody (HRP)
Primary AntibodyLSBio Guarantee
| Antibody: | Rabbit Polyclonal |
| Applications: | Enzyme-Linked Immunosorbent Assay |
| Reactivity: | Human |
| Format: | Liquid |
$300.00each
Catalog Number: LS-C501908-50
Catalog Number: LS-C501908
For bulk orders or custom formulations:
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- Description
- CARD15 antibody LS-C501908 is an HRP-conjugated rabbit polyclonal antibody to human CARD15 (NOD2). Validated for ELISA.
- Application
- ELISA
- Reactivity
- Hu
- Intended Use
- Research Use Only
- Guarantees
- This antibody carries the LSBio 100% Guarantee. ✓
- Category
- Antibodies > Primary Antibodies > Polyclonal Antibodies
- Alternative Names
- BLAU | CARD15 | ACUG | NOD-like receptor C2 | NOD2B | NLRC2 | IBD1 | NOD2 | CLR16.3 | PSORAS1
- UniProt Number
- Q9HC29
- NCBI GenBank
- NM_022162 | NP_071445.1
- SwissProt
- Q9HC29
Target
- Target
- Human NOD2 / CARD15
- Antigen Species
- Human
- Epitope
- Involved in gastrointestinal immunity. Upon stimulation by muramyl dipeptide (MDP), a fragment of bacterial peptidoglycan, binds the proximal adapter receptor-interacting RIPK2, which recruits ubiquitin ligases as XIAP, BIRC2, BIRC3 and the LUBAC complex, triggering activation of MAP kinases and activation of NF-kappa-B signaling. This in turn leads to the transcriptional activation of hundreds of genes involved in immune response. Required for MDP-induced NLRP1-dependent CASP1 activation and IL1B release in macrophages (PubMed:18511561).
- Gene Name
- NOD2
Antibody
- Host Species
- Rabbit
- Clonality
- Polyclonal
- Isotype
- IgG
Immunogen
- Immunogen
- Recombinant Human Nucleotide-binding oligomerization domain-containing protein 2 protein (460-733AA)
- Immunogen Type
- Recombinant Immunogen
Format
- Conjugate/Label
- Horseradish Peroxidase
- Format
- Liquid
- Formulation
- PBS, pH 7.4, 0.03% Proclin 300, 50% glycerol.
- Preservative
- Yes
- Purification Method
- Protein G Affinity
Storage & Handling
- Storage Conditions
- Short term: -20°C; Long term: -80°C; Avoid freeze-thaw cycles.
- Recommended Storage Buffer
- PBS