NCAM / CD56 Antibody (clone 123C3)
Primary AntibodyLSBio Guarantee
| Antibody: | Mouse Monoclonal |
| Applications: | Enzyme-Linked Immunosorbent Assay, Flow Cytometry, Immunohistochemistry (general), Immunohistochemistry, Frozen |
| Reactivity: | Human |
| Format: | Liquid |
$286.00each
Catalog Number: LS-C45020-0.1
Catalog Number: LS-C45020
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- Description
- CD56 antibody LS-C45020 is an unconjugated mouse monoclonal antibody to human CD56 (NCAM). Validated for ELISA, Flow and IHC.
- Application
- ELISA, FC, IHC, IHC-F
- Reactivity
- Hu
- Intended Use
- Research Use Only
- Guarantees
- This antibody carries the LSBio 100% Guarantee. ✓
- Category
- Antibodies > Primary Antibodies > Monoclonal Antibodies
- Alternative Names
- CD56 | CD56 antigen | MSK39 | NCAM-1 | N-CAM-1 | NCAM | NCAM1
- Recommended Dilution: FC
- 1:10
- UniProt Number
- P13591
- NCBI GenBank
- NM_000615 | NP_000606.3
- SwissProt
- P13591
Target
- Target
- Human NCAM / CD56
- Antigen Species
- Human
- Epitope
- Recognizes human neural cell adhesion molecule (NCAM), otherwise known as CD56. The CD56 molecule is a cell surface glycoprotein which is expressed on neuroendocrine cells, natural killer cells and a subset of T cells in the peripheral blood. Three main isoforms of CD56 exist. Neurons express the largest 180kD form, while hemopoietic cells express the 140kD isoform. Antibodies produced by clone 123C3 recognize the 140 and 180kD isoforms of the CD56 protein. In neuronal tissues, CD56 mediates homophilic and heterophilic adhesion and is implicated in neural development. Studies suggest that CD56 is also expressed on thyroid follicular epithelium and may play a role in autoimmune disease of the thyroid. CD56 is expressed in a range of tumors including tumors of the lung, neural derived malignancies and natural killer cell lymphomas.
- Gene Name
- NCAM1
Antibody
- Host Species
- Mouse
- Clonality
- Monoclonal
- Clone
- 123C3
- Isotype
- IgG1
Immunogen
- Immunogen
- Small cell lung carcinoma.
- Immunogen Type
- Cell-Based Immunization
Format
- Conjugate/Label
- Unconjugated
- Format
- Liquid
- Formulation
- PBS, 0.09% Sodium Azide
- Concentration
- 1 mg/mL
- Preservative
- Yes
- Purification Method
- Protein G Affinity
Storage & Handling
- Storage Conditions
- Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.
- Recommended Storage Buffer
- PBS