LSBio
PathPlus™ Recombinant Monoclonal Rabbit anti-Human NCAM / CD56 Antibody (clone NCAM1/2217R, IHC)

Human Cerebellum: Formalin-Fixed, Paraffin-Embedded (FFPE)

PathPlus™ Recombinant Monoclonal Rabbit anti-Human NCAM / CD56 Antibody (clone NCAM1/2217R, IHC)

Primary AntibodyLSBio Guarantee
Antibody:Rabbit Recombinant Monoclonal
Applications:Immunohistochemistry (general)
Reactivity:Human
Format:Liquid
See all NCAM / CD56 antibodies →
$536.00each
Catalog Number: LS-B16307-100

For bulk orders or custom formulations:

Request a Quote

Overview

Description
CD56 antibody LS-B16307 is an unconjugated rabbit recombinant monoclonal antibody to human CD56 (NCAM). Validated for IHC.
Application
IHC
Reactivity
Hu
Intended Use
Research Use Only
Guarantees
This product carries the LSBio 100% Guarantee.
Category
Antibodies > Primary Antibodies > Recombinant Antibodies
Alternative Names
CD56 | CD56 antigen | MSK39 | NCAM-1 | N-CAM-1 | NCAM | NCAM1
Recommended Dilution: IHC-P
1:200
UniProt Number
P13591
SwissProt
P13591

Target

Target
NCAM / CD56
Antigen Species
Human
Specificity
This MAb reacts with an extracellular domain (close to transmembrane) of CD56/NCAM. Three isoforms of neural cell adhesion molecule (NCAM) are produced by differential splicing of the RNA transcript from a single gene. The 135 kDa isoform is the basic molecule, which is glycosylated or sialylated to produce the mature species. Anti-CD56 recognizes two proteins of the neural cell adhesion molecule, the basic molecule expressed on most neuroectodermally derived tissues and neoplasms (e.g. retinoblastoma, medulloblastomas, astrocytomas, neuroblastomas, and small cell carcinomas). It is also expressed on some mesodermally derived tumors (rhabdomyosarcoma). Anti-CD56 plays an important role in the diagnosis of nodal and nasal NK/T-cell lymphomas.
Epitope
This MAb reacts with an extracellular domain (close to transmembrane) of CD56/NCAM. Three isoforms of neural cell adhesion molecule (NCAM) are produced by differential splicing of the RNA transcript from a single gene. The 135 kDa isoform is the basic molecule, which is glycosylated or sialylated to produce the mature species. Anti-CD56 recognizes two proteins of the neural cell adhesion molecule, the basic molecule expressed on most neuroectodermally derived tissues and neoplasms (e.g. retinoblastoma, medulloblastomas, astrocytomas, neuroblastomas, and small cell carcinomas). It is also expressed on some mesodermally derived tumors (rhabdomyosarcoma). Anti-CD56 plays an important role in the diagnosis of nodal and nasal NK/T-cell lymphomas.
Gene Name
NCAM1

Antibody

Host Species
Rabbit
Clonality
Recombinant Monoclonal
Clone
NCAM1/2217R
Origin Species
Human

Immunogen

Immunogen
Recombinant full-length human NCAM1 (CD56) protein. Antigen Molecular Weight: 180, 145 and 125 kDa
Immunogen Type
Full-Length Recombinant Protein

Format

Conjugate/Label
Unconjugated
Format
Liquid
Formulation
10 mM PBS, 0.05% BSA, 0.05% Sodium Azide
Concentration
200 µg/mL
Animal Free
No
Carrier-Free
No
Preservative
Yes
Purification Method
Protein A/G Affinity

Storage & Handling

Storage Conditions
Store at 2°C to 8°C for up to 2 years.
Recommended Storage Buffer
10 mM PBS

Request SDS/MSDS

To request an SDS/MSDS form for this product, please contact our Technical Support department at: technical@vectorlabs.com.