Monoclonal Rat anti-Mouse CD90.2 (Mouse) Antibody (clone 30H12, AF647)
Catalog Number: LS-C810655
2 sizes / from $259.00
Antibody: Rat Monoclonal
Applications: Flow Cytometry
Reactivity: Mouse
Format: Liquid
Monoclonal Mouse anti-Human CD300A Antibody (clone MEM-260, WB)
Primary AntibodyLSBio Guarantee
| Antibody: | Mouse Monoclonal |
| Applications: | Flow Cytometry, Immunohistochemistry (general), Western Blot |
| Reactivity: | Human |
| Format: | Liquid |
$286.00each
Catalog Number: LS-C45034-0.1
Catalog Number: LS-C45034
For bulk orders or custom formulations:
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- Description
- CD300A antibody LS-C45034 is an unconjugated mouse monoclonal antibody to human CD300A. Validated for Flow and WB.
- Application
- FC, IHC, WB
- Reactivity
- Hu
- Intended Use
- Research Use Only
- Guarantees
- This antibody carries the LSBio 100% Guarantee. ✓
- Category
- Antibodies > Primary Antibodies > Monoclonal Antibodies
- Alternative Names
- CD300A | CD300a antigen | CD300a molecule | CMRF35-like molecule 8 | CMRF35-H | CMRF35-H9 | CLM-8 | CMRF35H9 | IGSF12 | Inhibitory receptor protein 60 | IRC2 | IRC1 | NK inhibitory receptor | CMRF-35-H9 | CMRF-35H | CMRF35H | IRC1a | IRp60 | Leukocyte membrane antigen
- UniProt Number
- Q9UGN4
- NCBI GenBank
- NM_007261
- SwissProt
- Q9UGN4
Target
- Target
- Human CD300A
- Antigen Species
- Human
- Epitope
- Recognizes human CD300a, otherwise known as IRp60 (inhibitory receptor protein 60), a 60kD transmembrane glycoprotein expressed by natural killer cells (NK), T and B cell subsets, monocytes, neutrophils, macrophages, granulocytes, dendritic cells (DC) and mast cells. Studies have shown that the cross-linking of CD300a on NK results in a down-regulation of their cytolytic activity, whilst cross-linking of CD300a on mast cells, inhibits IgE-induced degranulation and SCF-mediated survival. Furthermore, cross-linking of CD300a on the surface of eosinophils has been shown to significantly inhibit their survival, chemotaxis and activation in response to certain inflammatory cytokines, whilst eosinophil-derived MBP (major basic protein) and EDN (neurotoxin), can down-regulate CD300a expression on mast cells in vitro.
- Gene Name
- CD300A
Antibody
- Host Species
- Mouse
- Clonality
- Monoclonal
- Clone
- MEM-260
- Isotype
- IgG1
Immunogen
- Immunogen
- Human HPB acute lymphoid leukaemia cell line.
- Immunogen Type
- Cell-Based Immunization
Format
- Conjugate/Label
- Unconjugated
- Format
- Liquid
- Formulation
- PBS, 0.09% Sodium Azide
- Concentration
- 1 mg/mL
- Preservative
- Yes
- Purification Method
- Protein A Affinity
Storage & Handling
- Storage Conditions
- Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.
- Recommended Storage Buffer
- PBS
