Monoclonal Hamster anti-Mouse CD81 Antibody (clone Eat2, FITC)
Primary AntibodyLSBio Guarantee
| Antibody: | Hamster Monoclonal |
| Applications: | Flow Cytometry |
| Reactivity: | Mouse |
| Format: | Liquid |
$335.00each
Catalog Number: LS-C43993-0.1
Catalog Number: LS-C43993
For bulk orders or custom formulations:
Request a QuoteOverview
- Description
- CD81 antibody LS-C43993 is an FITC-conjugated hamster monoclonal antibody to mouse CD81. Validated for Flow.
- Application
- FC
- Reactivity
- Ms
- Intended Use
- Research Use Only
- Guarantees
- This antibody carries the LSBio 100% Guarantee. ✓
- Category
- Antibodies > Primary Antibodies > Monoclonal Antibodies
- Alternative Names
- CD81 | CD81 antigen | CD81 molecule | CVID6 | S5.7 | TAPA1 | TAPA-1 | Tetraspanin-28 | TSPAN28 | Tspan-28
- UniProt Number
- P60033
- NCBI GenBank
- NM_004356 | NP_004347.1
- SwissProt
- P60033
Target
- Target
- Mouse CD81
- Antigen Species
- Mouse
- Epitope
- Recognizes mouse and rat CD81, also known as TAPA-1 or Target of the antiproliferative antibody 1. CD81 is a 236 amino acid ~26 kD multipass transmembrane protein belonging to the TM4SF family. In rodents CD81 is expressed at much higher levels on resting B cells than on T cells, although increased expression on T cells is found following activation. Induces homotypic aggregation of B cells and inhibits anti Ig and IL-4 induced proliferation. Eat 2 requires the presence of both extracellular loops of TAPA-1 for binding. Mice lacking CD81 demonstrate reduced fertility through impaired oocyte-sperm fusion, double knockout CD81-/- CD9-/- mice are completely infertile suggesting complementary roles in oocyte-sperm fusion.
- Gene Name
- CD81
Antibody
- Host Species
- Hamster
- Clonality
- Monoclonal
- Clone
- Eat2
- Isotype
- IgG1
Immunogen
- Immunogen
- 38C13, murine B cell line.
- Immunogen Type
- Cell-Based Immunization
Format
- Conjugate/Label
- Fluorescein Isothiocyanate
- Format
- Liquid
- Formulation
- PBS, 0.09% Sodium Azide, 1% BSA
- Concentration
- 0.1 mg/mL
- Preservative
- Yes
- Purification Method
- Protein G Affinity
Storage & Handling
- Storage Conditions
- Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Protect from light. Microcentrifugation recommended if solution contains precipitate.
- Recommended Storage Buffer
- PBS
