CD81 Antibody (clone Eat2)

Primary AntibodyLSBio Guarantee

Antibody:	Hamster Monoclonal
Applications:	Enzyme-Linked Immunosorbent Assay, Flow Cytometry, Immunohistochemistry (general), Immunohistochemistry, Frozen, Immunoprecipitation, Western Blot
Reactivity:	Mouse
Format:	Liquid

$286.00each

Catalog Number: LS-C43994-0.1

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Description: CD81 antibody LS-C43994 is an unconjugated hamster monoclonal antibody to mouse CD81. Validated for ELISA, Flow, IHC, IP and WB.
Application: ELISA, FC, IHC, IHC-F, IP, WB
Reactivity: Ms
Intended Use: Research Use Only
Guarantees: This antibody carries the LSBio 100% Guarantee. ✓
Category: Antibodies > Primary Antibodies > Monoclonal Antibodies
Alternative Names: CD81 | CD81 antigen | CD81 molecule | CVID6 | S5.7 | TAPA1 | TAPA-1 | Tetraspanin-28 | TSPAN28 | Tspan-28
Recommended Dilution: FC: 1:10 - 1:50
UniProt Number: P60033
NCBI GenBank: NM_004356 | NP_004347.1
SwissProt: P60033

Target: Mouse CD81
Antigen Species: Mouse
Epitope: Recognizes mouse and rat CD81, also known as TAPA-1 or Target of the antiproliferative antibody 1. CD81 is a 236 amino acid ~26 kD multipass transmembrane protein belonging to the TM4SF family. In rodents CD81 is expressed at much higher levels on resting B cells than on T cells, although increased expression on T cells is found following activation. Induces homotypic aggregation of B cells and inhibits anti Ig and IL-4 induced proliferation. Eat 2 requires the presence of both extracellular loops of TAPA-1 for binding. Mice lacking CD81 demonstrate reduced fertility through impaired oocyte-sperm fusion, double knockout CD81-/- CD9-/- mice are completely infertile suggesting complementary roles in oocyte-sperm fusion.
Gene Name: CD81

Storage Conditions: Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.
Recommended Storage Buffer: PBS