CD81 Antibody (clone Eat2)

Name: CD81 Antibody (clone Eat2)
Brand: LSBio
SKU: LS-C34594-250
Price: 389 USD
Availability: InStock

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$389.00each

Catalog Number: LS-C34594-250

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Description: CD81 antibody LS-C34594 is an unconjugated hamster monoclonal antibody to mouse CD81. Validated for Flow.
Application: FC
Reactivity: Ms
Intended Use: Research Use Only
Guarantees: This antibody carries the LSBio 100% Guarantee. ✓
Category: Antibodies > Primary Antibodies > Monoclonal Antibodies
Alternative Names: CD81 | CD81 antigen | CD81 molecule | CVID6 | S5.7 | TAPA1 | TAPA-1 | Tetraspanin-28 | TSPAN28 | Tspan-28
UniProt Number: P60033
NCBI GenBank: NM_004356 | NP_004347.1
SwissProt: P60033

Target: Mouse CD81
Antigen Species: Mouse
Epitope: Reacts with the extracellular loops of murine CD81 (TAPA-1) molecule. As a member of the tetraspanin superfamily of cell-surface proteins, CD81 has been linked to the control of cell proliferation, adhesion and motility. CD81 is expressed in higher levels on resting murine B cells than on resting T cells and is functionally active on B cells as it induces homotypic adhesion of B lymphocytes. Unlike human CD81, which is expressed equally on all thymocytes, murine CD81 is upregulated on CD4+CD8+ thymocytes, then down-regulated again on mature single-positive thymocytes. Murine dendritic cells, splenic macrophages and non-killer cells all express very high levels of CD81. CD81 has also been involved in the induction of IL-4 secretion from T cells during Th2 immune responses. It has been reported that CD81 expression can also be induced in mature T cells upon activation. This anti-CD81 mAb has been shown to decrease the proliferation of LPS stimulated CD81+/+ B cells to levels similar to that of CD81-/- B cells.
Gene Name: CD81

Storage Conditions: Store at 4°C for short term applications. For long term storage, aliquot and store at -20°C.
Recommended Storage Buffer: PBS