ITGB2 / CD18 Antibody (clone YFC118.3, RPE)
Primary AntibodyLSBio Guarantee
| Antibody: | Rat Monoclonal |
| Applications: | Flow Cytometry |
| Reactivity: | Human |
| Format: | Lyophilized |
$413.00each
Catalog Number: LS-C45162-100
Catalog Number: LS-C45162
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- Description
- CD18 antibody LS-C45162 is an RPE-conjugated rat monoclonal antibody to human CD18 (ITGB2). Validated for Flow.
- Application
- FC
- Reactivity
- Hu
- Intended Use
- Research Use Only
- Guarantees
- This antibody carries the LSBio 100% Guarantee. ✓
- Category
- Antibodies > Primary Antibodies > Monoclonal Antibodies
- Alternative Names
- CD18 antigen | CD18 | Integrin beta chain, beta 2 | ITGB2 | LCAMB | MAC-1 | MFI7 | MF17 | Integrin beta-2 | LAD | LFA-1
- Recommended Dilution: FC
- 1:1
- UniProt Number
- P05107
- NCBI GenBank
- NM_000211 | NP_000202.3
- SwissProt
- P05107
Target
- Target
- Human ITGB2 / CD18
- Antigen Species
- Human
- Epitope
- YFC118.3 was clustered at the Fourth International Workshop on Leucocyte Differentiation Antigen (code number N221) as recognizing the CD18 antigen. The CD18 antigen is an integral membrane glycoprotein of 95kD molecular weight - known as the b chain, of the LFA-1 complex. The CD18 antigen is non-covalently linked to CD11a, b, c molecules. The main cellular reactivity of antibody YFC 118.3 is a strong reactivity with Leucocytes (platelets negative). The CD18 molecule is the receptor for ICAM-1 and is thus important for cell adhesion. YFC118.3 blocks homotypic adhesion and other lymphocyte functions which involve the LFA-1 antigen.
- Gene Name
- ITGB2
Antibody
- Host Species
- Rat
- Clonality
- Monoclonal
- Clone
- YFC118.3
- Isotype
- IgG2b
Immunogen
- Immunogen
- Human neutrophils.
Format
- Conjugate/Label
- Phycoerythrin
- Format
- Lyophilized
- Formulation
- PBS, 0.09% Sodium Azide, 5% Sucrose, 1% BSA
- Preservative
- Yes
- Purification Method
- Protein G Affinity
Storage & Handling
- Storage Conditions
- Store at 4°C. Do not freeze. Store undiluted. Protect from light. Microcentrifugation recommended if solution contains precipitate.
- Recommended Storage Buffer
- PBS