ITGAM / CD11b Antibody (clone OX-42)

Primary AntibodyLSBio Guarantee

Antibody:	Mouse Monoclonal
Applications:	Immunohistochemistry (general), Immunohistochemistry, Frozen
Reactivity:	Rat
Format:	Liquid

$799.00each

Catalog Number: LS-C96404-1000

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Description: CD11b antibody LS-C96404 is an unconjugated mouse monoclonal antibody to rat CD11b (ITGAM). Validated for IHC.
Application: IHC, IHC-F
Reactivity: Rt
Intended Use: Research Use Only
Guarantees: This antibody carries the LSBio 100% Guarantee. ✓
Category: Antibodies > Primary Antibodies > Monoclonal Antibodies
Alternative Names: Antigen CD11b (p170) | CD11B | CD11b antigen | CR3A | Integrin alpha-M | MAC-1 | MO1A | Neutrophil adherence receptor | MAC1A | SLEB6 | CR-3 alpha chain | ITGAM
Recommended Dilution: IHC-F: 1:100 - 1:200
UniProt Number: P11215
NCBI GenBank: NM_000632 | NP_000623.2
SwissProt: P11215

Target: Rat ITGAM / CD11b
Antigen Species: Rat
Epitope: CD11b/c. OX-42 recognizes three major polypeptides of 160kDa, 103kDa and 95kDa and a minor 133kDa protein under non-reducing conditions. Under reducing conditions two major peptides of 163kDa and 100kDa and a minor 135kDa peptide are detected. Antigen distribution: Isolated cells: OX-42 shows a similar reaction pattern to OX-41 on various isolated cells but stains bronchial lavage cells to a lesser degree. OX-42 inhibits complement mediated rosettes. Tissue sections: OX-42 is a most suitable marker for the identification of microglial cells and Kupffer cells. It also stains dendritic cells strongly. Only a subpopulation of alveolar macrophages is recognised. Specificity: Rat: granulocytes, macrophages, microglial cells. Other species: not tested
Gene Name: ITGAM

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