ITGAM / CD11b Antibody (clone OX-42)
Primary AntibodyLSBio Guarantee
| Antibody: | Mouse Monoclonal |
| Applications: | Flow Cytometry, Immunofluorescence, Immunohistochemistry, Frozen, Immunoprecipitation |
| Reactivity: | Rat |
| Format: | Liquid |
$694.00each
Catalog Number: LS-C45063-1
Catalog Number: LS-C45063
For bulk orders or custom formulations:
Request a QuoteOverview
- Description
- CD11b antibody LS-C45063 is an unconjugated mouse monoclonal antibody to rat CD11b (ITGAM). Validated for Flow, IF, IHC and IP.
- Application
- FC, IF, IHC-F, IP
- Reactivity
- Rt
- Intended Use
- Research Use Only
- Guarantees
- This antibody carries the LSBio 100% Guarantee. ✓
- Category
- Antibodies > Primary Antibodies > Monoclonal Antibodies
- Alternative Names
- Antigen CD11b (p170) | CD11B | CD11b antigen | CR3A | Integrin alpha-M | MAC-1 | MO1A | Neutrophil adherence receptor | MAC1A | SLEB6 | CR-3 alpha chain | ITGAM
- Recommended Dilution: FC
- 1:50 - 1:100
- Recommended Dilution: IHC-F
- 1:50 - 1:100
- UniProt Number
- P11215
- NCBI GenBank
- NM_000632 | NP_000623.2
- SwissProt
- P11215
Target
- Target
- Rat ITGAM / CD11b
- Antigen Species
- Rat
- Epitope
- Recognizes the rat equivalent of human CD11b, the receptor for the iC3b component of complement. The antigen is expressed on most macrophages, including resident and activated peritoneal macrophages and Kupffer cells and around 35% of alveolar macrophages. The antibody also labels dendritic cells, granulocytes and microglial cells in the brain. Clone MRC OX-42 has been reported as being suitable for use on paraffin-embedded material following PLP fixation (periodate-lysine-paraformaldehyde). Functionally, clone OX-42 inhibits complement mediated rosettes(1). XXX recommend the use of MCA275EL for use in functional studies.
- Gene Name
- ITGAM
Antibody
- Host Species
- Mouse
- Clonality
- Monoclonal
- Clone
- OX-42
- Isotype
- IgG2a
Immunogen
- Immunogen
- Rat peritoneal macrophages
- Immunogen Type
- Cell-Based Immunization
Format
- Conjugate/Label
- Unconjugated
- Format
- Liquid
- Formulation
- PBS, 0.09% Sodium Azide
- Concentration
- 1 mg/mL
- Preservative
- Yes
- Purification Method
- Protein G Affinity
Storage & Handling
- Storage Conditions
- Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.
- Recommended Storage Buffer
- PBS