SMO / Smoothened Antibody
Catalog Number: LS-C408690
2 sizes / from $281.00
Antibody: Rabbit Polyclonal
Applications: Immunohistochemistry (general), Western Blot
Reactivity: Human, Mouse, Rat
Format: Liquid
Human Breast, Lobule: Formalin-Fixed, Paraffin-Embedded (FFPE)
IHC-plus™ SMO / Smoothened Antibody (aa68-117)
Primary AntibodyLSBio Guarantee
| Antibody: | Rabbit Polyclonal |
| Applications: | Enzyme-Linked Immunosorbent Assay, Immunohistochemistry (general), Immunohistochemistry, Paraffin, Western Blot |
| Reactivity: | Human, Mouse, Rat |
| Format: | Liquid |
$470.00each
Catalog Number: LS-B4911-50
Catalog Number: LS-B4911
For bulk orders or custom formulations:
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- Description
- Smoothened antibody LS-B4911 is an unconjugated rabbit polyclonal antibody to Smoothened (SMO) (aa68-117) from human. It is reactive with human, mouse and rat. Validated for IHC, Peptide-ELISA and WB. Tested on 20 paraffin-embedded human tissues. Cited in 2 publications.
- Application
- ELISA, IHC, IHC-P, WB
- Reactivity
- Hu, Ms, Rt
- Intended Use
- Research Use Only
- Guarantees
- This product carries the LSBio 100% Guarantee. ✓
- Category
- Antibodies > Primary Antibodies > Polyclonal Antibodies
- Alternative Names
- Frizzled family member 11 | FZD11 | Gx | Protein Gx | SMOH | Smoothened | SMO | Smoothened homolog
- Recommended Dilution: IHC-P
- 5 - 10 µg/ml
- Recommended Dilution: WB
- 1:500 - 1:1000
- UniProt Number
- Q99835
- NCBI GenBank
- NM_005631 | NP_005622.1
- SwissProt
- Q99835
Target
- Target
- SMO / Smoothened
- Antigen Species
- Human
- Specificity
- SMO Antibody detects endogenous levels of total SMO protein.
- Epitope
- SMO Antibody detects endogenous levels of total SMO protein.
- Gene Name
- SMO
Antibody
- Host Species
- Rabbit
- Clonality
- Polyclonal
- Origin Species
- Human
Immunogen
- Immunogen
- Synthetic peptide from human SMO. (AA Range: 68-117)
- Immunogen Type
- Synthetic Peptide (Linear)
Format
- Conjugate/Label
- Unconjugated
- Format
- Liquid
- Formulation
- PBS (without Mg2+, Ca2+), pH 7.4, 150 mM NaCl, 0.02% Sodium Azide, 50% Glycerol
- Concentration
- 1 mg/mL
- Volume
- 50 Microliter
- Animal Free
- No
- Carrier-Free
- Yes
- Preservative
- Yes
- Purification Method
- Affinity Purified
Storage & Handling
- Storage Conditions
- Store at -20°C for up to 1 year.
- Recommended Storage Buffer
- PBS, 150 mM NaCl
Hedgehog signalling pathway activation in gastrointestinal stromal tumours is mediated by primary cilia. Pablo Iruzubieta, Marta Monzón, Tomás Castiella, Teresa Ramírez, Concepción Junquera. Gastric Cancer : official journal of the international Gastric Cancer Association and the Japanese Gastric Cancer Association. 2019 Jan;23:64-72.
PubMed: 31267361
Stromal cells of giant cell tumor of bone show primary cilia in giant cell tumor of bone. Tomás Castiella, Pablo Iruzubieta, Eva Monleón, Mª José Cardiel, Jesús Gómez-Vallejo, Marta Monzón, Mª Concepción Junquera. Microscopy research and technique. 2022 March;85:1065-1074.
PubMed: 34761465
