LSBio
IHC-plus™ SIRT1 / Sirtuin 1 Antibody (clone 7B7)

Anti-SIRT1 antibody IHC of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.

IHC-plus™ SIRT1 / Sirtuin 1 Antibody (clone 7B7)

Primary AntibodyLSBio Guarantee
Antibody:Mouse Monoclonal
Applications:Enzyme-Linked Immunosorbent Assay, Immunofluorescence, Immunohistochemistry (general), Immunohistochemistry, Paraffin, Western Blot
Reactivity:Human
Format:Liquid
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$470.00each
Catalog Number: LS-B4520-50

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Overview

Description
Sirtuin 1 antibody LS-B4520 is an unconjugated mouse monoclonal antibody to human Sirtuin 1 (SIRT1). Validated for ELISA, IF, IHC and WB. Tested on 20 paraffin-embedded human tissues. Cited in 1 publication.
Application
ELISA, IF, IHC, IHC-P, WB
Reactivity
Hu
Intended Use
Research Use Only
Guarantees
This product carries the LSBio 100% Guarantee.
Category
Antibodies > Primary Antibodies > Monoclonal Antibodies
Alternative Names
SIR2-like protein 1 | SIR2alpha | SIR2L1 | Sirtuin 1 | Sir2-like 1 | SIRT1 | Sirtuin type 1 | HSIR2 | HSIRT1
Recommended Dilution: IF/ICC
10 µg/ml
Recommended Dilution: IHC-P
5 µg/ml
UniProt Number
Q96EB6
SwissProt
Q96EB6

Target

Target
SIRT1 / Sirtuin 1
Antigen Species
Human
Gene Name
SIRT1

Antibody

Host Species
Mouse
Clonality
Monoclonal
Clone
7B7
Light Chain
Kappa Light Chain
Origin Species
Human

Immunogen

Immunogen
SIRT1 (AAH12499, 456 aa ~ 555 aa) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Format

Conjugate/Label
Unconjugated
Format
Liquid
Formulation
PBS, pH 7.4
Concentration
0.5 mg/mL
Animal Free
No
Carrier-Free
Yes
Purification Method
Protein A Affinity

Storage & Handling

Storage Conditions
Store at 4°C or -20°C. Avoid freeze-thaw cycles.
Recommended Storage Buffer
PBS
Age-Associated Sirtuin 1 Reduction in Vascular Smooth Muscle Links Vascular Senescence and Inflammation to Abdominal Aortic Aneurysm. Chen HZ, Wang F, Gao P, Pei JF, Liu Y, Xu TT, Tang X, Fu WY, Lu J, Yan YF, Wang XM, Han L, Zhang ZQ, Zhang R, Zou MH, Liu DP. Circulation research. 2016 October;119:1076-1088. PubMed: 27650558

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