LSBio
IHC-plus™ PTCH1 / Patched 1 Antibody (aa1431-1442)

Anti-PTCH1 antibody IHC of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 3.75 ug/ml.

IHC-plus™ PTCH1 / Patched 1 Antibody (aa1431-1442)

Primary AntibodyLSBio Guarantee
Antibody:Goat Polyclonal
Applications:Enzyme-Linked Immunosorbent Assay, Immunofluorescence, Immunohistochemistry (general), Immunohistochemistry, Paraffin
Reactivity:Dog, Horse, Human, Mammal (Other), Non-Human Primate
Format:Liquid
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$383.00each
Catalog Number: LS-B3939-50

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Overview

Description
Patched 1 antibody LS-B3939 is an unconjugated goat polyclonal antibody to Patched 1 (PTCH1) (aa1431-1442) from human. It is reactive with human, bat, dog and other species. Validated for IF, IHC and Peptide-ELISA. Tested on 20 paraffin-embedded human tissues. Cited in 1 publication.
Application
ELISA, IF, IHC, IHC-P
Reactivity
Can, Hr, Hu, Mml, NHP
Intended Use
Research Use Only
Guarantees
This product carries the LSBio 100% Guarantee.
Category
Antibodies > Primary Antibodies > Polyclonal Antibodies
Alternative Names
NBCCS | Patched 1 | Patched homolog 1 | Protein patched homolog 1 | PTC1 | PTCH | PTCH protein +12b | PTCH protein -10 | PTCH protein -3 | 4 | 5 | Patched | Patched protein homolog 1 | PTCH1 | BCNS | HPE7 | Patched homolog | PTC | PTCH protein +4 | PTCH11
Recommended Dilution: IF/ICC
5 µg/ml
Recommended Dilution: IHC-P
3.75 µg/ml
UniProt Number
Q13635
SwissProt
Q13635

Target

Target
PTCH1 / Patched 1
Antigen Species
Human
Specificity
Human PTCH1. This antibody is expected to recognise all reported isoforms. Variants (NP_001077073.1; NP_001077074.1; NP_001077075.1; NP_001077076.1) encode the same isoform.
Epitope
Human PTCH1. This antibody is expected to recognise all reported isoforms. Variants (NP_001077073.1; NP_001077074.1; NP_001077075.1; NP_001077076.1) encode the same isoform.
Gene Name
PTCH1

Antibody

Host Species
Goat
Clonality
Polyclonal
Origin Species
Human

Immunogen

Immunogen
Peptide with sequence ELQDVECEERPR, from the C-Terminus of protein sequence according to NP_000255.1NP_001077072.1NP_001077071.1NP_001077073.1NP_001077074.1NP_001077075.1NP_001077076.1.
Immunogen Type
Peptide

Format

Conjugate/Label
Unconjugated
Format
Liquid
Formulation
TBS, pH 7.3, 0.02% Sodium Azide, 0.5% BSA
Concentration
0.5 mg/mL
Animal Free
No
Carrier-Free
No
Preservative
Yes
Purification Method
Ammonium Sulfate Precipitation

Storage & Handling

Storage Conditions
Aliquot and store at -20°C. Avoid freeze-thaw cycles.
Recommended Storage Buffer
TBS
Ptch2 loss drives myeloproliferation and myeloproliferative neoplasm progression. Klein C, Zwick A, Kissel S, Forster CU, Pfeifer D, Follo M, Illert AL, Decker S, Benkler T, Pahl H, Oostendorp RA, Aumann K, Duyster J, Dierks C. The Journal of experimental medicine. 2016;213:273-90. PubMed: 26834157 PMC: PMC4749921

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