PTCH1 staining in Xenopus retina. Paraformaldehyde-fixed Xenopus retina is stained with PTCH1 Antibody used at a 1:200 dilution (from Gordon et al. 2010).
PTCH1 / Patched 1 Antibody
Primary AntibodyLSBio Guarantee
| Antibody: | Rabbit Polyclonal |
| Applications: | Enzyme-Linked Immunosorbent Assay, Immunofluorescence, Immunohistochemistry (general), Western Blot |
| Reactivity: | Human, Mouse, Rat |
| Format: | Liquid |
$402.00each
Catalog Number: LS-C413720-0.1
Catalog Number: LS-C413720
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- Description
- Patched 1 antibody LS-C413720 is an unconjugated rabbit polyclonal antibody to Patched 1 (PTCH1) from human. It is reactive with human, mouse and rat. Validated for ELISA, IF, IHC and WB.
- Application
- ELISA, IF, IHC, WB
- Reactivity
- Hu, Ms, Rt
- Intended Use
- Research Use Only
- Guarantees
- This antibody carries the LSBio 100% Guarantee. ✓
- Category
- Antibodies > Primary Antibodies > Polyclonal Antibodies
- Alternative Names
- NBCCS | Patched 1 | Patched homolog 1 | Protein patched homolog 1 | PTC1 | PTCH | PTCH protein +12b | PTCH protein -10 | PTCH protein -3,4,5 | Patched | Patched protein homolog 1 | PTCH1 | BCNS | HPE7 | Patched homolog | PTC | PTCH protein +4 | PTCH11
- Recommended Dilution: ELISA
- 1:500 - 1:1000
- Recommended Dilution: IF/ICC
- 1:100 - 1:500
- Recommended Dilution: WB
- 1:100 - 1:500
- UniProt Number
- Q13635
- NCBI GenBank
- NM_000264 | NP_000255.2
- SwissProt
- Q13635
Target
- Target
- Human PTCH1 / Patched 1
- Antigen Species
- Human
- Epitope
- PTCH1 is a receptor for sonic hedgehog, indian hedgehog and desert hedgehog that associates with the smoothened protein to transduce the hedgehog's protein signal. Defects in PTCH1 are the cause of several structural anomalies of the brain such as the basal cell nevus syndrome and holoprosencephaly type 7.
- Gene Name
- PTCH1
Antibody
- Host Species
- Rabbit
- Clonality
- Polyclonal
Immunogen
- Immunogen
- KLH-conjugated synthetic peptide from the C-Terminus of human PTCH1.
- Immunogen Type
- Synthetic Peptide (Linear)
Format
- Conjugate/Label
- Unconjugated
- Format
- Liquid
- Formulation
- PBS, pH 7.4, 0.09% sodium azide, 15% glycerol.
- Preservative
- Yes
- Purification Method
- Protein A Affinity
Storage & Handling
- Storage Conditions
- Store at -20°C. Avoid freeze-thaw cycles.
- Recommended Storage Buffer
- PBS