LSBio
IHC-plus™ NOVA1 Antibody (aa121-134)

Anti-NOVA1 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.

IHC-plus™ NOVA1 Antibody (aa121-134)

Primary AntibodyLSBio Guarantee
Antibody:Goat Polyclonal
Applications:Enzyme-Linked Immunosorbent Assay, Immunohistochemistry (general), Immunohistochemistry, Paraffin, Western Blot
Reactivity:Bovine, Dog, Chicken, Human, Mammal (Other), Mouse, Non-Human Primate, Pig, Rabbit, Rat, Xenopus
Format:Liquid
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$495.00each
Catalog Number: LS-B3259-50

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Overview

Description
NOVA1 antibody LS-B3259 is an unconjugated goat polyclonal antibody to NOVA1 (aa121-134) from human. It is reactive with human, mouse, rat and other species. Validated for IHC, Peptide-ELISA and WB. Tested on 20 paraffin-embedded human tissues. Cited in 2 publications.
Application
ELISA, IHC, IHC-P, WB
Reactivity
Bov, Can, Ck, Hu, Mml, Ms, NHP, Por, Rb, Rt, Xen
Intended Use
Research Use Only
Guarantees
This product carries the LSBio 100% Guarantee.
Category
Antibodies > Primary Antibodies > Polyclonal Antibodies
Alternative Names
Nova-1 | Onconeural ventral antigen 1 | RNA-binding protein Nova-1 | NOVA1 | Paraneoplastic Ri antigen
Recommended Dilution: IHC-P
2.5 µg/ml
Recommended Dilution: WB
0.01 - 0.03 µg/ml
UniProt Number
P51513
SwissProt
P51513

Target

Target
NOVA1
Antigen Species
Human
Specificity
Human NOVA1. This antibody is expected to recognise all three reported isoforms (NP_002506.2 ; NP_006480.2 ; NP_006482.1)
Epitope
Human NOVA1. This antibody is expected to recognise all three reported isoforms (NP_002506.2 ; NP_006480.2 ; NP_006482.1)
Gene Name
NOVA1

Antibody

Host Species
Goat
Clonality
Polyclonal
Origin Species
Human

Immunogen

Immunogen
Peptide with sequence C-REMPQNVAKTEPVS, from the internal region of the protein sequence according to NP_002506.2 NP_006480.2 NP_006482.1.
Immunogen Type
Peptide

Format

Conjugate/Label
Unconjugated
Format
Liquid
Formulation
TBS, pH 7.3, 0.02% Sodium Azide, 0.5% BSA
Concentration
0.5 mg/mL
Animal Free
No
Carrier-Free
No
Preservative
Yes
Purification Method
Ammonium Sulfate Precipitation

Storage & Handling

Storage Conditions
Aliquot and store at -20°C. Avoid freeze-thaw cycles.
Recommended Storage Buffer
TBS

High expression of neuro-oncological ventral antigen 1 correlates with poor prognosis in hepatocellular carcinoma. Zhang YA, Zhu JM, Yin J, Tang WQ, Guo YM, Shen XZ, Liu TT. PloS one. 2014;9:e90955.

PubMed: 24608171 · PMC: PMC3946567


RNA binding protein Nova1 promotes tumor growth in vivo and its potential mechanism as an oncogene may due to its interaction with GABAA Receptor-?2. Zhang YA, Liu HN, Zhu JM, Zhang DY, Shen XZ, Liu TT. Journal of biomedical science. 2016;23:71.

PubMed: 27733149 · PMC: PMC5062898

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