HIF1A / HIF1 Alpha Antibody (clone HIF1A-84)
Catalog Number: LS-C357910
2 sizes / from $379.00
Antibody: Mouse Monoclonal
Applications: Enzyme-Linked Immunosorbent Assay, Flow Cytometry, Immunofluorescence
Reactivity: Human
Format: Liquid
Anti-HIF1A antibody IHC of human kidney, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100. This image was taken for the unconjugated form of this product. Other forms have not been tested.
IHC-plus™ HIF1A / HIF1 Alpha Antibody (aa432-528)
Primary AntibodyLSBio Guarantee
| Antibody: | Rabbit Polyclonal |
| Applications: | Immunohistochemistry (general), Immunohistochemistry, Paraffin, Western Blot |
| Reactivity: | Dog, Guinea Pig, Human, Mouse, Non-Human Primate, Rat, Xenopus, Zebrafish |
| Format: | Liquid |
$383.00each
Catalog Number: LS-B2823-0.1
Catalog Number: LS-B2823
For bulk orders or custom formulations:
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- Description
- HIF1 Alpha antibody LS-B2823 is an unconjugated rabbit polyclonal antibody to HIF1 Alpha (HIF1A) (aa432-528) from human. It is reactive with human, mouse, rat and other species. Validated for IHC and WB. Tested on 20 paraffin-embedded human tissues. Cited in 2 publications.
- Application
- IHC, IHC-P, WB
- Reactivity
- Can, GP, Hu, Ms, NHP, Rt, Xen, Zf
- Intended Use
- Research Use Only
- Guarantees
- This product carries the LSBio 100% Guarantee. ✓
- Category
- Antibodies > Primary Antibodies > Polyclonal Antibodies
- Alternative Names
- ARNT-interacting protein | ARNT interacting protein | BHLHe78 | HIF1 Alpha | HIF1A | Hypoxia-inducible factor1alpha | HIF-1A | HIF1 | MOP1 | Member of PAS superfamily 1 | PASD8 | HIF-1-alpha | HIF-1alpha | HIF1-ALPHA | Member of PAS protein 1
- Recommended Dilution: IHC-P
- 1:100
- UniProt Number
- Q16665
- NCBI GenBank
- NM_001530 | NP_001521.1
- SwissProt
- Q16665
Target
- Target
- HIF1A / HIF1 Alpha
- Antigen Species
- Human
- Specificity
- HIF-1 alpha.
- Epitope
- HIF-1 alpha.
- Gene Name
- HIF1A
Antibody
- Host Species
- Rabbit
- Clonality
- Polyclonal
- Origin Species
- Human
Immunogen
- Immunogen
- Fusion protein containing amino acids 432-528 of human HIF-1 alpha [UniProt# Q16665]
- Immunogen Type
- Fusion Protein (e.g., GST, MBP tag)
Format
- Conjugate/Label
- Unconjugated
- Format
- Liquid
- Formulation
- PBS, 0.05% Sodium Azide
- Concentration
- 1 mg/mL
- Volume
- 0.1 Milliliter
- Animal Free
- No
- Carrier-Free
- Yes
- Preservative
- Yes
- Purification Method
- Affinity Purified
Storage & Handling
- Storage Conditions
- Short term: store at 4°C. Long term: aliquot and store at -20°C. Avoid freeze-thaw cycles.
- Recommended Storage Buffer
- PBS
Hypoxia-independent upregulation of placental hypoxia inducible factor-1a gene expression contributes to the pathogenesis of preeclampsia. Iriyama T, Wang W, Parchim NF, Song A, Blackwell SC, Sibai BM, Kellems RE, Xia Y. Hypertension. 2015;65:1307-15.
PubMed: 25847948 · PMC: PMC4859813
Reciprocal upregulation of hypoxia-inducible factor-1a and persistently enhanced placental adenosine signaling contribute to the pathogenesis of preeclampsia. Takayuki Iriyama, Wei Wang, Nicholas F Parchim, Seisuke Sayama, Keiichi Kumasawa, Takeshi Nagamatsu, Anren Song, Yang Xia, Rodney E Kellems. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 2020 March;34:4041-4054.
PubMed: 31930569 · PMC: PMC7060108
