CYBB / NOX2 / gp91phox Antibody
Catalog Number: LS-C335167
2 sizes / from $281.00
Antibody: Rabbit Polyclonal
Applications: Immunofluorescence, Immunohistochemistry (general), Western Blot
Reactivity: Human, Mouse, Rat
Format: Liquid
Human Brain, Cerebellum: Formalin-Fixed, Paraffin-Embedded (FFPE)
IHC-plus™ CYBB / NOX2 / gp91phox Antibody (aa471-510)
Primary AntibodyLSBio Guarantee
| Antibody: | Rabbit Polyclonal |
| Applications: | Immunohistochemistry (general), Immunohistochemistry, Paraffin, Western Blot |
| Reactivity: | Human, Mouse, Rat |
| Format: | Liquid |
$470.00each
Catalog Number: LS-B12365-50
Catalog Number: LS-B12365
For bulk orders or custom formulations:
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- Description
- Gp91phox antibody LS-B12365 is an unconjugated rabbit polyclonal antibody to gp91phox (CYBB / NOX2) (aa471-510) from human. It is reactive with human, mouse and rat. Validated for IHC and WB. Tested on 20 paraffin-embedded human tissues. Cited in 3 publications.
- Application
- IHC, IHC-P, WB
- Reactivity
- Hu, Ms, Rt
- Intended Use
- Research Use Only
- Guarantees
- This product carries the LSBio 100% Guarantee. ✓
- Category
- Antibodies > Primary Antibodies > Polyclonal Antibodies
- Alternative Names
- Chronic granulomatous disease | CGD91-phox | Cytochrome b558 subunit beta | Cytochrome b(558) subunit beta | CYBB | gp91-1 | gp91-PHOX | p22 phagocyte B-cytochrome | AMCBX2 | CGD | Cytochrome b-245 heavy chain | gp91PHOX | NADPH oxidase 2 | NOX2 | p91-PHOX
- Recommended Dilution: IHC-P
- 1:200
- Recommended Dilution: WB
- 1:500 - 1:1000
- UniProt Number
- P04839
- NCBI GenBank
- NM_000397 | NP_000388.2
- SwissProt
- P04839
Target
- Target
- CYBB / NOX2 / gp91phox
- Antigen Species
- Human
- Specificity
- Human GP91PHOX / NOX2
- Epitope
- Human GP91PHOX / NOX2
- Gene Name
- CYBB
Antibody
- Host Species
- Rabbit
- Clonality
- Polyclonal
- Origin Species
- Human
Immunogen
- Immunogen
- Synthetic peptide around Ile502 of human GP91PHOX / NOX2
- Immunogen Type
- Synthetic Peptide (Linear)
Format
- Conjugate/Label
- Unconjugated
- Format
- Liquid
- Formulation
- PBS, pH 7.2, 0.05% Sodium Azide, 50% Glycerol
- Volume
- 50 Microliter
- Animal Free
- No
- Carrier-Free
- Yes
- Preservative
- Yes
- Purification Method
- Affinity Purified
Storage & Handling
- Storage Conditions
- Short term: store at 4°C. Long term: aliquot and store at -20°C. Avoid freeze-thaw cycles.
- Recommended Storage Buffer
- PBS
Ablation of lysozyme M-positive cells prevents aircraft noise-induced vascular damage without improving cerebral side effects. Katie Frenis, Johanna Helmstädter, Yue Ruan, Eva Schramm, Sanela Kalinovic, Swenja Kröller-Schön, Maria Teresa Bayo Jimenez, Omar Hahad, Matthias Oelze, Subao Jiang, Philip Wenzel, Clemens J Sommer, Katrin B M Frauenknecht, Ari Waisman, Adrian Gericke, Andreas Daiber, Thomas Münzel , Sebastian Steven. Basic research in cardiology. 2021 April;116:31.
PubMed: 33929610 · PMC: PMC8087569
GLP-1 Analog Liraglutide Improves Vascular Function in Polymicrobial Sepsis by Reduction of Oxidative Stress and Inflammation. Johanna Helmstädter, Karin Keppeler, Franziska Aust, Leonie Küster, Katie Frenis, Konstantina Filippou, Ksenija Vujacic-Mirski, Simeon Tsohataridis, Sanela Kalinovic, Swenja Kröller-Schön, Matthias Oelze, Markus Bosmann , Thomas Münzel , Andreas Daiber , Sebastian Steven. Antioxidants. 2021 Jul;10:1175.
PubMed: 34439423 · PMC: PMC8388926
Long-Term Effects of Aircraft Noise Exposure on Vascular Oxidative Stress, Endothelial Function and Blood Pressure: No Evidence for Adaptation or Tolerance Development. Katie Frenis, Sanela Kalinovic, Benjamin P Ernst, Miroslava Kvandova, Ahmad Al Zuabi, Marin Kuntic, Matthias Oelze, Paul Stamm, Maria Teresa Bayo Jimenez, Agnieszka Kij, Karin Keppeler, Veronique Klein, Lea Strohm, Henning Ubbens, Steffen Daub, Omar Hahad, Swenja Kröller-Schön, Michael J Schmeisser, Stefan Chlopicki, Jonas Eckrich, Sebastian Strieth, Andreas Daiber, Sebastian Steven, Thomas Münzel. Frontiers in molecular biosciences. 2022 February;8:814921.
PubMed: 35174211 · PMC: PMC8841864
