CYBB / NOX2 / gp91phox Antibody (clone 7D5)
| Antibody: | Mouse Monoclonal |
| Applications: | Flow Cytometry, Immunohistochemistry (general) |
| Reactivity: | Human |
| Format: | Liquid |
For bulk orders or custom formulations:
Request a QuoteOverview
- Description
- Gp91phox antibody LS-C179418 is an unconjugated mouse monoclonal antibody to human gp91phox (CYBB / NOX2). Validated for Flow. Cited in 2 publications.
- Application
- FC, IHC
- Reactivity
- Hu
- Intended Use
- Research Use Only
- Guarantees
- This antibody carries the LSBio 100% Guarantee. ✓
- Category
- Antibodies > Primary Antibodies > Monoclonal Antibodies
- Alternative Names
- Chronic granulomatous disease | CGD91-phox | Cytochrome b558 subunit beta | Cytochrome b(558) subunit beta | CYBB | gp91-1 | gp91-PHOX | p22 phagocyte B-cytochrome | AMCBX2 | CGD | Cytochrome b-245 heavy chain | gp91PHOX | NADPH oxidase 2 | NOX2 | p91-PHOX
- UniProt Number
- P04839
- NCBI GenBank
- NM_000397 | NP_000388.2
- SwissProt
- P04839
Target
- Target
- Human CYBB / NOX2 / gp91phox
- Antigen Species
- Human
- Epitope
- Human GP91PHOX / NOX2
- Gene Name
- CYBB
Antibody
- Host Species
- Mouse
- Clonality
- Monoclonal
- Clone
- 7D5
- Isotype
- IgG1
Immunogen
- Immunogen
- Rich fraction of human cytochrome b
Format
- Conjugate/Label
- Unconjugated
- Format
- Liquid
- Formulation
- PBS, pH 7.2, 50% Glycerol, No preservatives added
- Concentration
- 1 mg/mL
- Preservative
- No
Storage & Handling
- Storage Conditions
- Store at -20°C for 1 year.
- Recommended Storage Buffer
- PBS
Constitutive activation of WASp in X-linked neutropenia renders neutrophils hyperactive. Keszei M, Record J, Kritikou JS, Wurzer H, Geyer C, Thiemann M, Drescher P, Brauner H, Köcher L, James J, He M, Baptista MA, Dahlberg CI, Biswas A, Lain S, Lane DP, Song W, Pütsep K, Vandenberghe P, Snapper SB, Westerberg LS. The Journal of clinical investigation. 2018 August;128:4115-4131.
PubMed: 30124469 · PMC: PMC6118594
Guidelines for the Detection of NADPH Oxidases by Immunoblot and RT-qPCR. Becky A Diebold, S Garrett Wilder, Xavier De Deken, Jennifer L Meitzler, James H Doroshow, James W McCoy, Yerun Zhu, J David Lambeth. Methods in molecular biology (Clifton, N.J.). 2019 June;1982:191-229.
PubMed: 31172474 · PMC: PMC8132109