EDNRB / Endothelin B Receptor Antibody (aa424-437)
Primary AntibodyLSBio Guarantee
| Antibody: | Sheep Polyclonal |
| Applications: | Immunofluorescence, Immunohistochemistry (general), Immunohistochemistry, Paraffin, Immunoprecipitation |
| Reactivity: | Rat |
| Format: | Liquid |
$296.00each
Catalog Number: LS-C187726-0.1
Catalog Number: LS-C187726
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- Description
- Endothelin B Receptor antibody LS-C187726 is an unconjugated sheep polyclonal antibody to rat Endothelin B Receptor (EDNRB) (aa424-437). Validated for IF, IHC and IP.
- Application
- IF, IHC, IHC-P, IP
- Reactivity
- Rt
- Intended Use
- Research Use Only
- Guarantees
- This antibody carries the LSBio 100% Guarantee. ✓
- Category
- Antibodies > Primary Antibodies > Polyclonal Antibodies
- Alternative Names
- ABCDS | Endothelin B receptor | EDNRB | Etb receptor | ET-B | Et-b receptor | Et-b-r | ET-RB | ETBR | ETRB | Etb-svr | WS4A | Endothelin receptor type B | ET-BR | ETB | HSCR | HSCR2
- Recommended Dilution: IHC-P
- 10 - 20 µg/ml
- UniProt Number
- P24530
- NCBI GenBank
- NM_000115 | NP_000106.1
- SwissProt
- P24530
Target
- Target
- Rat EDNRB / Endothelin B Receptor
- Antigen Species
- Rat
- Epitope
- Recognizes an epitope within the C-terminal (CT) region of endothelin B receptor (ET-B), a widely distributed transmembrane protein and member of the G-protein coupled receptor 1 family, which acts as a non-specific receptor for endothelin 1, 2, and 3, and mediates its action by G protein association and activation of a phosphatidylinositol-calcium second messenger system. AAR43 recognizes epitopes on the cytoplasmic side of the receptor and therefore the cell membrane must be permeable to the antibody. AAR43 does not block the binding of endothelins. AAR43 is reported as suitable for use in immunocytochemistry on acetone fixed cells.
- Gene Name
- EDNRB
Antibody
- Host Species
- Sheep
- Clonality
- Polyclonal
- Isotype
- IgG
Immunogen
- Immunogen
- Keyhole limpet hemocyanin (KLH) conjugated C-Terminus peptide KANDHGYDNFRSSNN corresponding to amino acids 424 to 437 of rat endothelin B receptor. Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Orangutan, Gibbon, Monkey, Galago, Marmoset, Mouse, Rat, Ferret, Sheep, Goat, Hamster, Elephant, Panda, Cat, Bovine, Dog, Horse, Rabbit, Pig, Opossum, Zebra finch, Chicken, Platypus (93%); Lizard (87%).
- Immunogen Type
- Peptide
Format
- Conjugate/Label
- Unconjugated
- Format
- Liquid
- Formulation
- PBS, less than 0.1% Sodium Azide
- Concentration
- 1.41 mg/mL
- Preservative
- Yes
- Purification Method
- Affinity Purified
Storage & Handling
- Storage Conditions
- Store at 4°C. Do not freeze. Store undiluted. Microcentrifugation recommended if solution contains precipitate.
- Recommended Storage Buffer
- PBS