LSBio
PathPlus™ EDNRB / Endothelin B Receptor Antibody (N-Terminus)

Anti-EDNRB antibody IHC of human adrenal, medulla. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

PathPlus™ EDNRB / Endothelin B Receptor Antibody (N-Terminus)

Primary AntibodyLSBio Guarantee
Antibody:Rabbit Polyclonal
Applications:Immunohistochemistry (general)
Reactivity:Dog, Human
Format:Liquid
See all EDNRB / Endothelin B Receptor antibodies →
$449.00each
Catalog Number: LS-A54-50

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Overview

Description
Endothelin B Receptor antibody LS-A54 is an unconjugated rabbit polyclonal antibody to Endothelin B Receptor (EDNRB) (N-Terminus) from human. It is reactive with human and dog. Validated for ICC, IHC and WB. Cited in 2 publications.
Application
IHC
Reactivity
Can, Hu
Intended Use
Research Use Only
Guarantees
This product carries the LSBio 100% Guarantee. ✓
Category
Antibodies > Primary Antibodies > Polyclonal Antibodies
Alternative Names
ABCDS | Endothelin B receptor | EDNRB | Etb receptor | ET-B | Et-b receptor | Et-b-r | ET-RB | ETBR | ETRB | Etb-svr | WS4A | Endothelin receptor type B | ET-BR | ETB | HSCR | HSCR2
Recommended Dilution: IHC-P
4 - 11 µg/ml
UniProt Number
P24530
NCBI GenBank
NM_000115 | NP_000106.1
SwissProt
P24530

Target

Target
EDNRB / Endothelin B Receptor
Antigen Species
Human
Specificity
Human EDNRB. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except PTPN5 (68%).
Epitope
Human EDNRB. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except PTPN5 (68%).
Gene Name
EDNRB

Antibody

Host Species
Rabbit
Clonality
Polyclonal

Immunogen

Immunogen
Synthetic 19 amino acid peptide from N-Terminus extracellular domain of human EDNRB. Percent identity with other species by BLAST analysis: Human, Dog (100%); Gorilla, Gibbon (95%); Monkey (89%); Marmoset (84%).
Immunogen Type
Synthetic Peptide (Linear)

Format

Conjugate/Label
Unconjugated
Format
Liquid
Formulation
PBS, 0.1% Sodium Azide
Concentration
1 mg/mL
Animal Free
No
Carrier-Free
Yes
Preservative
Yes
Purification Method
Affinity Purified

Storage & Handling

Storage Conditions
Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze-thaw cycles.
Recommended Storage Buffer
PBS

Role of beta-galactosidase and elastin binding protein in lysosomal and nonlysosomal complexes of patients with GM1-gangliosidosis. Caciotti A, Donati MA, Boneh A, d'Azzo A, Federico A, Parini R, Antuzzi D, Bardelli T, Nosi D, Kimonis V, Zammarchi E, Morrone A. Human mutation. 2005 Mar;25:285-92.

PubMed: 15714521

Endothelin B receptor expression correlates with tumour angiogenesis and prognosis in oesophageal squamous cell carcinoma. Tanaka T, Sho M, Takayama T, Wakatsuki K, Matsumoto S, Migita K, Ito M, Hamada K, Nakajima Y. British journal of cancer. 2014 Feb;110:1027-33.

PubMed: 24357795 · PMC: PMC3929870

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