Immunofluorescent analysis of HepG2 cells using DIAPH3 Antibody at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
DIAPH3 / MDIA2 Antibody
Primary AntibodyLSBio Guarantee
| Antibody: | Rabbit Polyclonal |
| Applications: | Enzyme-Linked Immunosorbent Assay, Immunofluorescence |
| Reactivity: | Human |
| Format: | Liquid |
$300.00each
Catalog Number: LS-C502031-50
Catalog Number: LS-C502031
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- Description
- MDIA2 antibody LS-C502031 is an unconjugated rabbit polyclonal antibody to human MDIA2 (DIAPH3). Validated for ELISA and IF.
- Application
- ELISA, IF
- Reactivity
- Hu
- Intended Use
- Research Use Only
- Guarantees
- This antibody carries the LSBio 100% Guarantee. ✓
- Category
- Antibodies > Primary Antibodies > Polyclonal Antibodies
- Alternative Names
- AUNA1 | DRF3 | Diap3 | Diaphanous-related formin-3 | DIA2 | DIAPH3 | MDia2 | NSDAN | Protein diaphanous homolog 3
- UniProt Number
- Q9NSV4
- NCBI GenBank
- NM_030932 | NP_112194.2
- SwissProt
- Q9NSV4
Target
- Target
- Human DIAPH3 / MDIA2
- Antigen Species
- Human
- Epitope
- Binds to GTP-bound form of Rho and to profilin. Acts in a Rho-dependent manner to recruit profilin to the membrane, where it promotes actin polymerization. It is required for cytokinesis, stress fiber formation, and transcriptional activation of the serum response factor. DFR proteins couple Rho and Src tyrosine kinase during signaling and the regulation of actin dynamics (By similarity).
- Gene Name
- DIAPH3
Antibody
- Host Species
- Rabbit
- Clonality
- Polyclonal
- Isotype
- IgG
Immunogen
- Immunogen
- Recombinant Human Protein diaphanous homolog 3 protein (642-849AA)
- Immunogen Type
- Recombinant Immunogen
Format
- Conjugate/Label
- Unconjugated
- Format
- Liquid
- Formulation
- PBS, pH 7.4, 0.03% Proclin 300, 50% glycerol.
- Concentration
- 4 mg/mL
- Preservative
- Yes
- Purification Method
- Protein G Affinity
Storage & Handling
- Storage Conditions
- Short term: -20°C; Long term: -80°C; Avoid freeze-thaw cycles.
- Recommended Storage Buffer
- PBS