CD86 Antibody (clone 24F)

Primary AntibodyLSBio Guarantee

Antibody:	Mouse Monoclonal
Applications:	Flow Cytometry, Immunohistochemistry (general), Immunohistochemistry, Frozen, Immunoprecipitation
Reactivity:	Rat
Format:	Liquid

$415.00each

Catalog Number: LS-C188424-0.25

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Description: CD86 antibody LS-C188424 is an unconjugated mouse monoclonal antibody to rat CD86. Validated for Flow, IHC and IP.
Application: FC, IHC, IHC-F, IP
Reactivity: Rt
Intended Use: Research Use Only
Guarantees: This antibody carries the LSBio 100% Guarantee. ✓
Category: Antibodies > Primary Antibodies > Monoclonal Antibodies
Alternative Names: Activation B7-2 antigen | B7-2 | B7.2 | B70 | CD86 molecule | CD86 | CTLA-4 counter-receptor B7.2 | CD86 antigen | FUN-1 | LAB72 | BU63 | CD28LG2 | Ctla-4 counter-receptors b7.2
Recommended Dilution: FC: 1:25 - 1:200
UniProt Number: P42081
NCBI GenBank: NM_006889 | NP_008820.3
SwissProt: P42081

Target: Rat CD86
Antigen Species: Rat
Epitope: Recognizes rat CD86, otherwise known as B7-2, a type I transmembrane protein and member of the Ig superfamily, which acts as a ligand for both CD28 and CD152 (CTLA-4), and is primarily expressed on antigen presenting cells (APCs) including dendritic cells, and also on germinal centre B cells and macrophages. Like CD80, CD86 is an accessory molecule which functions in the CD28-CD80/CD86 co-stimulatory pathway, vital for T cell activation, crosstalk between T and B cells, and Th2-mediated Ig production. Clone 24F has been shown to block the co-stimulatory activity of rat CD86.
Gene Name: CD86

Storage Conditions: Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.
Recommended Storage Buffer: PBS