Western blot analysis of CARD11 expression in K562 (A); Ramos (B); Jurkat (C) whole cell lysates.
CARMA1 / CARD11 Antibody (N-Terminus)
| Antibody: | Rabbit Polyclonal |
| Applications: | Immunocytochemistry, Immunofluorescence, Immunohistochemistry (general), Immunohistochemistry, Paraffin, Western Blot |
| Reactivity: | Human, Mouse |
| Format: | Liquid |
For bulk orders or custom formulations:
Request a QuoteOverview
- Description
- CARD11 antibody LS-C368868 is an unconjugated rabbit polyclonal antibody to CARD11 (CARMA1) (N-Terminus) from human. It is reactive with human and mouse. Validated for ICC, IF, IHC and WB. Cited in 2 publications.
- Application
- ICC, IF, IHC, IHC-P, WB
- Reactivity
- Hu, Ms
- Intended Use
- Research Use Only
- Guarantees
- This antibody carries the LSBio 100% Guarantee. ✓
- Category
- Antibodies > Primary Antibodies > Polyclonal Antibodies
- Alternative Names
- Card-maguk protein 1 | CARMA1 | Carma 1 | BIMP3 | CARD11
- Recommended Dilution: IF/ICC
- 1:100 - 1:500
- Recommended Dilution: IHC-P
- 1:100 - 1:200
- Recommended Dilution: WB
- 1:500 - 1:1000
- UniProt Number
- Q9BXL7
- NCBI GenBank
- NM_032415 | NP_115791.3
- SwissProt
- Q9BXL7
Target
- Target
- Human CARMA1 / CARD11
- Antigen Species
- Human
- Epitope
- Recognizes endogenous levels of CARD11 protein.
- Gene Name
- CARD11
Antibody
- Host Species
- Rabbit
- Clonality
- Polyclonal
Immunogen
- Immunogen
- KLH-conjugated synthetic peptide encompassing a sequence within the N-Terminus of human CARD11.
- Immunogen Type
- Synthetic Peptide (Linear)
Format
- Conjugate/Label
- Unconjugated
- Format
- Liquid
- Formulation
- PBS, pH 7.3, 0.01% Sodium Azide, 30% Glycerol
- Concentration
- 1 mg/mL
- Volume
- 30 Microliter
- Preservative
- Yes
- Purification Method
- Affinity Purified
Storage & Handling
- Storage Conditions
- Aliquot and store at -20°C for 1 year. Avoid freeze/thaw cycles.
- Recommended Storage Buffer
- PBS
Omenn syndrome associated with a functional reversion due to a somatic second-site mutation in CARD11 deficiency. Fuchs S, Rensing-Ehl A, Pannicke U, Lorenz MR, Fisch P, Jeelall Y, Rohr J, Speckmann C, Vraetz T, Farmand S, Schmitt-Graeff A, Krüger M, Strahm B, Henneke P, Enders A, Horikawa K, Goodnow C, Schwarz K, Ehl S. Blood. 2015;126:1658-69.
PubMed: 26289640 · PMC: PMC4654427
Hypomorphic caspase activation and recruitment domain 11 (CARD11) mutations associated with diverse immunologic phenotypes with or without atopic disease. Batsukh Dorjbal, Jeffrey R Stinson, Chi A Ma, Michael A Weinreich, Bahar Miraghazadeh, Julia M Hartberger, Stefanie Frey-Jakobs, Stephan Weidinger, Lena Moebus, Andre Franke, Alejandro A Schäffer, Alla Bulashevska, Sebastian Fuchs, Stephan Ehl, Sandhya Limaye, Peter D Arkwright, Tracy A Briggs, Claire Langley, Claire Bethune, Andrew F Whyte, Hana Alachkar, Sergey Nejentsev, Thomas DiMaggio, Celeste G Nelson, Kelly D Stone, Martha Nason, Erica H Brittain, Andrew J Oler, Daniel P Veltri, T Ronan L. The Journal of allergy and clinical immunology. 2019 April;143:1482-1495.
PubMed: 30170123 · PMC: PMC6395549