LSBio
IHC-plus™ GZMB / Granzyme B Antibody (aa10-59)

Anti-GZMB / Granzyme B antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.

IHC-plus™ GZMB / Granzyme B Antibody (aa10-59)

Primary AntibodyLSBio Guarantee
Antibody:Rabbit Polyclonal
Applications:Enzyme-Linked Immunosorbent Assay, Immunohistochemistry (general), Immunohistochemistry, Paraffin, Western Blot
Reactivity:Human, Mouse, Rat
Format:Liquid
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$383.00each
Catalog Number: LS-B7602-50

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Overview

Description
Granzyme B antibody LS-B7602 is an unconjugated rabbit polyclonal antibody to Granzyme B (GZMB) (aa10-59) from human. It is reactive with human, mouse and rat. Validated for IHC, Peptide-ELISA and WB. Tested on 20 paraffin-embedded human tissues. Cited in 2 publications.
Application
ELISA, IHC, IHC-P, WB
Reactivity
Hu, Ms, Rt
Intended Use
RUO
Guarantees
This product carries the LSBio 100% Guarantee. ✓
Category
Antibodies > Primary Antibodies > Polyclonal Antibodies
Alternative Names
CCPI | CGL-1 | Cathepsin G-like 1 | CSP-B | CTLA-1 | CTLA1 | CGL1 | CSPB | Fragmentin 2 | GRB | HLP | Human lymphocyte protein | Fragmentin-2 | GZMB | SECT | Lymphocyte protease | T-cell serine protease 1-3E | C11 | CTSGL1 | Cytotoxic serine protease B | Granzyme B | Granzyme-2
Recommended Dilution: IHC-P
1:200
Recommended Dilution: WB
1:500 - 1:1000
UniProt Number
P10144
SwissProt
P10144

Target

Target
GZMB / Granzyme B
Antigen Species
Hu
Specificity
Granzyme B Antibody detects endogenous levels of total Granzyme B protein.
Epitope
Granzyme B Antibody detects endogenous levels of total Granzyme B protein.
Gene Name
GZMB

Antibody

Host Species
Rb
Clonality
Polyclonal
Origin Species
Hu

Immunogen

Immunogen
Synthetic peptide from human Granzyme B. (AA Range: 8-59)

Format

Conjugate/Label
Unconj
Format
Liquid
Formulation
PBS (without Mg2+, Ca2+), pH 7.4, 150 mM NaCl, 0.02% Sodium Azide, 50% Glycerol
Concentration
1 mg/mL
Volume
50 Microliter
Animal Free
No
Carrier-Free
Yes
Preservative
Yes
Purification Method
AP

Storage & Handling

Storage Conditions
Store at -20°C for up to 1 year.
Recommended Storage Buffer
PBS
Graft-versus-host disease propagation depends on increased intestinal epithelial tight junction permeability. Nalle SC, Zuo L, Ong MLDM, Singh G, Worthylake AM, Choi W, Manresa MC, Southworth AP, Edelblum KL, Baker GJ, Joseph NE, Savage PA, Turner JR. The Journal of clinical investigation. 2019 February;129:902-914. PubMed: 30667372 PMC: PMC6355225

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