Anti-OXGR1 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
IHC-plus™ GPR80 / GPR99 / OXGR1 Antibody (Extracellular Domain)
| Antibody: | Rabbit Polyclonal |
| Applications: | Immunohistochemistry (general) |
| Reactivity: | Human |
| Format: | Liquid |
For bulk orders or custom formulations:
Request a QuoteOverview
- Description
- OXGR1 antibody LS-A1865 is an unconjugated rabbit polyclonal antibody to human OXGR1 (GPR80 / GPR99) (Extracellular Domain). Validated for ELISA and IHC. Tested on 20 paraffin-embedded human tissues. Cited in 2 publications.
- Application
- IHC
- Reactivity
- Hu
- Predicted Reactivity
- Mouse, Non-Human Primate, Rabbit, Rat
- Intended Use
- Research Use Only
- Guarantees
- This product carries the LSBio 100% Guarantee. ✓
- Category
- Antibodies > Primary Antibodies > Polyclonal Antibodies
- Alternative Names
- 2-oxoglutarate receptor 1 | Alpha-ketoglutarate receptor 1 | G protein-coupled receptor 80 | GPR80 | G-protein coupled receptor 99 | GPR99 | OXGR1 | p2Y purinoceptor 15 | p2Y-like nucleotide receptor | p2RY15 | Oxoglutarate receptor 1 | p2Y-like GPCR | p2Y15 | G protein-coupled receptor 99 | G-protein coupled receptor 80
- Recommended Dilution: IHC-P
- 15 - 20 µg/ml
- UniProt Number
- Q96P68
- NCBI GenBank
- NM_080818 | NP_543008.3
- SwissProt
- Q96P68
Target
- Target
- GPR80 / GPR99 / OXGR1
- Antigen Species
- Human
- Specificity
- Human OXGR1. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
- Epitope
- Human OXGR1. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
- Gene Name
- OXGR1
Antibody
- Host Species
- Rabbit
- Clonality
- Polyclonal
Immunogen
- Immunogen
- Synthetic 17 amino acid peptide from 2nd extracellular domain of human OXGR1. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Marmoset (100%); Monkey, Mouse, Rat, Rabbit (94%); Dog, Bat, Hamster, Panda, Horse (88%).
- Immunogen Type
- Synthetic Peptide (Linear)
Format
- Conjugate/Label
- Unconjugated
- Format
- Liquid
- Formulation
- PBS, 0.1% Sodium Azide
- Concentration
- 1 mg/mL
- Animal Free
- No
- Carrier-Free
- Yes
- Preservative
- Yes
- Purification Method
- Affinity Purified
Storage & Handling
- Storage Conditions
- Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze-thaw cycles.
- Recommended Storage Buffer
- PBS
alpha -Ketoglutarate regulates acid-base balance through an intrarenal paracrine mechanism. Tokonami N, Morla L, Centeno G, Mordasini D, Ramakrishnan SK, Nikolaeva S, Wagner CA, Bonny O, Houillier P, Doucet A, Firsov D. The Journal of clinical investigation. 2013 Jul;123:3166-71.
PubMed: 23934124 · PMC: PMC3696567
Exercise-induced a-ketoglutaric acid stimulates muscle hypertrophy and fat loss through OXGR1-dependent adrenal activation. Yexian Yuan , Pingwen Xu , Qingyan Jiang , Xingcai Cai, Tao Wang, Wentong Peng, Jiajie Sun, Canjun Zhu, Cha Zhang, Dong Yue, Zhihui He, Jinping Yang, Yuxian Zeng, Man Du, Fenglin Zhang, Lucas Ibrahimi, Sarah Schaul, Yuwei Jiang, Jiqiu Wang, Jia Sun, Qiaoping Wang, Liming Liu, Songbo Wang, Lina Wang, Xiaotong Zhu, Ping Gao, Qianyun Xi, Cong Yin, Fan Li, Guli Xu, Yongliang Zhang, Gang Shu. The EMBO journal. 2020 Apr;39:e103304.
PubMed: 32104923 · PMC: PMC7110140