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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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DCLRE1A / SNM1 Antibody (aa1032‑1044) IHC‑plus™ LS‑B1758 Best Seller
Note: This antibody replaces LS-C47556
SNM1 antibody LS-B1758 is an unconjugated goat polyclonal antibody to human SNM1 (DCLRE1A). Validated for IHC and Peptide-ELISA. Tested on 20 paraffin-embedded human tissues.
Catalog
Size
Price
LS-B1758-50
50 µg (0.5 mg/ml)
$425

Popular DCLRE1A / SNM1 Products

Anti-DCLRE1A / SNM1 antibody IHC of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B1759 concentration 5 ug/ml.
Species: Human
Applications: IHC, IHC - Paraffin, Peptide Enzyme-Linked Immunosorbent Assay
Antibody
Species: Human
Applications: Western blot, Immunoprecipitation
Western blot analysis of extracts of various cell lines, using DCLRE1A antibody at 1:3000 dilution. The secondary antibody used was an HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates were loaded 25ug per lane and 3% nonfat dry milk in TBST was used for blocking. An ECL Kit was used for detection and the exposure time was 30s.
Species: Human
Applications: Western blot
Antibody
Species: Human
Applications: Immunoprecipitation

Product Description

SNM1 antibody LS-B1758 is an unconjugated goat polyclonal antibody to human SNM1 (DCLRE1A). Validated for IHC and Peptide-ELISA. Tested on 20 paraffin-embedded human tissues.
About DCLRE1A / SNM1
May be required for DNA interstrand cross-link repair. Also required for checkpoint mediated cell cycle arrest in early prophase in response to mitotic spindle poisons. Q6PJP8 D42045 BAA07646.2

DCLRE1A Antibody, DNA-crosslink repair gene SNM1 Antibody, HSNM1A Antibody, HSNM1 Antibody, KIAA0086 Antibody, PSO2 Antibody, SNM1 Antibody, SNM1A Antibody, PSO2 homolog Antibody, SNM1 homolog A Antibody, DNA cross-link repair 1A Antibody


Specifications

Target
Human DCLRE1A / SNM1
Host
Goat
Reactivity
Human (tested or 100% immunogen sequence identity)
Predicted
Monkey, Bovine, Dog, Horse (at least 90% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • IHC
  • IHC - Paraffin (2.5 µg/ml)
  • Peptide Enzyme-Linked Immunosorbent Assay (1:16000)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
DCLRE1A / SNM1 antibody was raised against synthetic peptide C-EKYFREWKLEAGY from the C-terminus of human DCLRE1A / SNM1 (NP_055696.3). Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey (100%); Marmoset, Bovine, Dog, Panda, Horse (92%); Mouse, Rat, Bat, Hamster, Elephant, Rabbit (85%).
Blocking Peptide
LS-E25717 - Lyophilized - 100 µg - $145.00
Immunizing peptide used to generate LS-B1758. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
Epitope
aa1032-1044
Specificity
Human DCLRE1A / SNM1.
Usage
Immunohistochemistry: LS-B1758 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B1758 was determined to be 2.5 ug/ml.
Presentation
TBS, pH 7.3, 0.02% Sodium Azide, 0.5% BSA
Storage
Store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.

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Images

Immunohistochemistry

Anti-DCLRE1A / SNM1 antibody IHC of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B1758 concentration 5 ug/ml.
Anti-DCLRE1A / SNM1 antibody IHC of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B1758 concentration 5 ug/ml.

Immunohistochemistry

Anti-DCLRE1A / SNM1 antibody IHC of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B1758 concentration 5 ug/ml.
Anti-DCLRE1A / SNM1 antibody IHC of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B1758 concentration 5 ug/ml.

Immunohistochemistry

Anti-DCLRE1A / SNM1 antibody IHC of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B1758 concentration 5 ug/ml.
Anti-DCLRE1A / SNM1 antibody IHC of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B1758 concentration 5 ug/ml.

Immunohistochemistry

Anti-DCLRE1A / SNM1 antibody IHC of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B1758 concentration 5 ug/ml.
Anti-DCLRE1A / SNM1 antibody IHC of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B1758 concentration 5 ug/ml.

Requested From: United States
Date Requested: 9/19/2018

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