IL6 / Interleukin 6 Antibody
Catalog Number: LS-C104444-500
500 µg / $333.00
Antibody: Mouse Monoclonal
Applications: Enzyme-Linked Immunosorbent Assay, Western Blot
Reactivity: Human
Format: Lyophilized
Biological Activity IL-6, Human stimulates cell proliferation of 7TD1 cells.The ED 50 for this effect is less than 0.06ng/mL.
Human IL6 / Interleukin 6 Protein (Recombinant)
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| Expression System | Chinese Hamster Ovary |
| Format: | Lyophilized |
$279.00each
Catalog Number: LS-G27203-10
Catalog Number: LS-G27203
For bulk orders or custom formulations:
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- Description
- Interleukin-6 (IL-6), also known as BSF-2, CDF and IFNB2, is a pleiotropic cytokine that acts in both pro-inflammatory and anti-inflammatory responses. It is produced mainly by T cells, macrophages, monocytes, endothelial cells and muscle cells. IL-6 binds to IL-6 receptor (IL-6R) to trigger the association of IL-6R with gp130, inducing signal transduction through JAKs and STATs. The biological functions of IL-6 are diverse. It stimulates B cell differentiation and antibody production, myeloma and plasmacytoma growth, as well as nerve cell differentiation. It also acts as a myokine, produced by muscle cells in response to muscle contraction, to be released to the blood stream to help break down fats and improve insulin resistance.
- Category
- Proteins & Peptides > Proteins > Recombinant Proteins
- Alternative Names
- B-cell stimulatory factor 2 | BSF-2 | BSF2 | CTL differentiation factor | Hybridoma growth factor | IFN-beta-2 | IL6 | Interleukin-6 | Interleukin BSF-2 | IFNB2 | B-cell differentiation factor | CDF | HSF | IL-6
- Origin Species
- Human
- NCBI GenBank
- NM_000600|NP_000591.1
- SwissProt
- P05231
Protein
- Expression System
- Chinese Hamster Ovary
- Molecular Weight
- 21-23 kDa (SDS-PAGE)
- Protein Type
- Recombinant
- Amino Acid Sequence
1PVPPGEDSKD VAAPHRQPLT SSERIDKQIR YILDGISALR KETCNKSNMC ESSKEALAEN61NLNLPKMAEK DGCFQSGFNE ETCLVKIITG LLEFEVYLEY LQNRFESSEE QARAVQMSTK121VLIQFLQKKA KNLDAITTPD PTTNASLLTK LQAQNQWLQD MTTHLILRSF KEFLQSSLRA181LRQM
184 aa
Format
- Purity
- >95%
- Conjugate/Label
- Unconjugated
- Endotoxin Level
- < 0.2 EU/µg
- Format
- Lyophilized
- Formulation
- Lyophilized from PBS
- Purity Measurement Method
- SDS-PAGE (Coomassie Stain)
Storage & Handling
- Storage Conditions
- Stable at -80°c for up to 6 months. Upon reconstitution, store at 4°c for up to 1 week or at -20°c for up to 2 months.
