Human IGF1 Protein (Recombinant)

Overview

Description

The Insulin-like growth factor-1(IGF-1) is mitogenic polypeptide growth factors that stimulate the proliferation and survival of various cell types including muscle, bone, and cartilage tissue in vitro. IGF-1 is predominantly produced by the liver, although a variety of tissues produce the IGFs at distinctive times. The IGF-1 belongs to the insulin gene family, which also contains insulin and relaxin. The IGF-1 is similar by structure and function to insulin, but have a much higher growth-promoting activity than insulin. This recombinant human IGF-I is globular protein containing 70 amino acids, and 3 intra-molecular disulfide bonds. Recombinant IGF-1 was expressed in E.coli and purified by conventional chromatography, after refolding of the isolated inclusion bodies in a renaturation buffer.

Category

Proteins & Peptides > Proteins > Recombinant Proteins

Alternative Names

IGF-IA | IGF-IB | IGFI | IBP1 | IGF-I | IGF1 | Insulin-like growth factor 1 | Insulin-like growth factor I | Insulin-like growth factor IA | Insulin-like growth factor IB | Mechano growth factor | Somatomedin-C | IGF1A | MGF

Origin Species

Hu

NCBI GenBank

NM_000618, NP_000609.1

SwissProt

P05019