LSBio
Human FLT3LG / Flt3 Ligand Protein (Recombinant)

Human FLT3LG / Flt3 Ligand Protein (Recombinant)

ProteinLSBio Guarantee
Expression SystemChinese Hamster Ovary
Format:Lyophilized
See all FLT3LG antibodies →
$302.00each
Catalog Number: LS-G27053-10

For bulk orders or custom formulations:

Request a Quote

Overview

Description
Fms-related tyrosine kinase 3 ligand (Flt3L) is growth factor stimulates the proliferation and differentiation of hematopoietic multipotent progenitors and promotes proliferation of NK cells and dendritic cell subgroups by combination with other growth factors. Flt3L is produced by T cells and stromal fibroblasts, and targeted various cells including hematopoietic stem cells, B cells, T cells, dendritic cells, and NK cells. Flt3L binds to it cognate tyrosine kinase receptor Flt3 and activates JAK/STAT signaling pathway.Flt3L is a hematopoietic four helical bundle cytokine with structurally homologous to stem cell factor (SCF) and colony stimulating facor 1 (CSF-1) demonstrated four conserved cysteines and two glycosylation sites. Flt3L naturally as a non-disulfide-linked homodimer with multiple isoforms. The extracellular portion is approximately 160 amino acid residues in length and the cytoplasmic segment is approximately 20-30 amino acid residues in length.
Category
Proteins & Peptides > Proteins > Recombinant Proteins
Alternative Names
FL | Flt3 ligand | FLT3LG | FLT3L | SL cytokine
Origin Species
Human
NCBI GenBank
NM_001459|NP_001450.2
SwissProt
P49771

Protein

Expression System
Chinese Hamster Ovary
Molecular Weight
18~22 kDa (SDS-PAGE)
Protein Type
Recombinant
Amino Acid Sequence
1TQDCSFQHSP ISSDFAVKIR ELSDYLLQDY PVTVASNLQD EELCGGLWRL VLAQRWMERL
61KTVAGSKMQG LLERVNTEIH FVTKCAFQPP PSCLRFVQTN ISRLLQETSE QLVALKPWIT
121RQNFSRCLEL QCQPDSSTLP PPWSPRPLEA TAPTA

155 aa

Format

Purity
>95%
Conjugate/Label
Unconjugated
Endotoxin Level
< 0.2 EU/µg
Format
Lyophilized
Formulation
Lyophilized from PBS
Purity Measurement Method
SDS-PAGE (Coomassie Stain)

Storage & Handling

Storage Conditions
Stable at -80°c for up to 6 months. Upon reconstitution, store at 4°c for up to 1 week or at -20°c for up to 2 months.

Request SDS/MSDS

To request an SDS/MSDS form for this product, please contact our Technical Support department at: technical@vectorlabs.com.