PTN / Pleiotrophin Antibody
Catalog Number: LS-C402762
4 sizes / from $260.00
Antibody: Rabbit Polyclonal
Applications: Enzyme-Linked Immunosorbent Assay, Immunohistochemistry (general), Western Blot
Reactivity: Human, Mouse, Rat
Format: Liquid
Mouse PTN / Pleiotrophin Protein (Recombinant 6His, C-terminus)
ProteinLSBio Guarantee
| Expression System | Other |
| Format: | Lyophilized |
$275.00each
Catalog Number: LS-G137885-10
Catalog Number: LS-G137885
For bulk orders or custom formulations:
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- Description
- Pleiotrophin (PTN) is a secreted, strongly heparinbinding, developmentally regulated cytokine. PTN is a highly conserved protein,Human, mouse, rat, canine, porcine, equine and bovine PTN share 98% aa sequence identity or greater. PTN and midkine share 50% amino acid (aa) sequence identity, share some functions, and constitute a family. During development, PTN is involved in development of brain, bone, and organs undergoing branching morphogenesis. PTN causes PTPRB dimerization and inactivates its phosphatase activity, which allows increased tyrosine phosphorylation of its substrates. Increased expression of PTN is correlated with neuronal development or stresses such as brain ischemia and Parkinson's disease.
- Category
- Proteins & Peptides > Proteins > Recombinant Proteins
- Alternative Names
- HARP | HBGF-8 | HBNF | HB-GAM | HBBM | HBNF-1 | Pleiotrophin | PTN | OSF-1 | Osteoblast-specific factor 1 | HBGF8 | HBNF1 | NEGF1
- Origin Species
- Mouse
- NCBI GenBank
- NM_002825
- SwissProt
- P21246
Protein
- Expression System
- Other
- Fusion Tag
- Hexahistidine Tag
- Protein Type
- Recombinant
- Amino Acid Sequence
1GKKEKPEKKV KKSDCGEWQW SVCVPTSGDC GLGTREGTRT GAECKQTMKT QRCKIPCNWK61KQFGAECKYQ FQAWGECDLN TALKTRTGSL KRALHNADCQ KTVTISKPCG KLTKPKPQAE121SKKKKKEGKK QEKMLDHHHH HH
142 aa
Format
- Purity
- >95%
- Conjugate/Label
- Unconjugated
- Endotoxin Level
- < 1 EU/µg
- Format
- Lyophilized
- Formulation
- Lyophilized from a sterile solution in PBS, pH 7.4.
- Purity Measurement Method
- SDS-PAGE (Coomassie Stain)
Storage & Handling
- Storage Conditions
- Before reconstitution: short term; store at room temperature for up to 3 weeks, long term; store at -20°C. After Reconstitution: short term; store at 4°C to 7°C for up to 7 days, long term; Aliquot and store at -20°C for up to 3 months. Avoid freeze-thaw cycles.
