LSBio
Mouse MARCO Protein (Recombinant 8His, N-terminus)

Mouse MARCO Protein (Recombinant 8His, N-terminus)

ProteinLSBio Guarantee
Expression SystemOther
Format:Lyophilized
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$275.00each
Catalog Number: LS-G137905-10

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Overview

Description
MARCO (macrophage receptor with collagenous structure) is an 80 kDa type II transmembrane glycoprotein that belongs to the class A scavenger receptor family. Mouse MARCO consists of a 48 amino acid (aa) cytoplasmic domain, a 21 aa transmembrane segment, and a 449 aa extracellular domain (ECD) that includes a stalk region, a collagenlike region, and one SRCR domain. MARCO is constitutively expressed on the surface of splenic and lymph node macrophages. MARCO binds LPS, lipoteichoic acid, and other determinants on Gram positive and Gram negative bacteria. It also binds modified LDL, CpG oligonucleotides, UGRP1, silica, and TiO2.
Category
Proteins & Peptides > Proteins > Recombinant Proteins
Alternative Names
MARCO | Macrophage receptor MARCO | Macrophage receptors marco | SCARA2
Origin Species
Mouse
NCBI GenBank
NM_006770
SwissProt
Q9UEW3

Protein

Expression System
Other
Fusion Tag
Octahistidine Tag
Protein Type
Recombinant
Amino Acid Sequence
1HHHHHHHHQV LNLQEQLQML EMCCGNGSLA IEDKPFFSLQ WAPKTHLVPR AQGLQALQAQ
61LSWVHTSQEQ LRQQFNNLTQ NPELFQIKGE RGSPGPKGAP GAPGIPGLPG PAAEKGEKGA
121AGRDGTPGVQ GPQGPPGSKG EAGLQGLTGA PGKQGATGAP GPRGEKGSKG DIGLTGPKGE
181HGTKGDKGDL GLPGNKGDMG MKGDTGPMGS PGAQGGKGDA GKPGLPGLAG SPGVKGDQGK
241PGVQGVPGPQ GAPGLSGAKG EPGRTGLPGP AGPPGIAGNP GIAGVKGSKG DTGIQGQKGT
301KGESGVPGLV GRKGDTGSPG LAGPKGEPGR VGQKGDPGMK GSSGQQGQKG EKGQKGESFQ
361RVRIMGGTNR GRAEVYYNNE WGTICDDDWD NNDATVFCRM LGYSRGRALS SYGGGSGNIW
421LDNVNCRGTE NSLWDCSKNS WGNHNCVHNE DAGVECS

457 aa

Format

Purity
>95%
Conjugate/Label
Unconjugated
Endotoxin Level
< 1 EU/µg
Format
Lyophilized
Formulation
Lyophilized from a sterile solution in PBS, pH 7.4.
Purity Measurement Method
SDS-PAGE (Coomassie Stain)

Storage & Handling

Storage Conditions
Before reconstitution: short term; store at room temperature for up to 3 weeks, long term; store at -20°C. After Reconstitution: short term; store at 4°C to 7°C for up to 7 days, long term; Aliquot and store at -20°C for up to 3 months. Avoid freeze-thaw cycles.

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