Measured by its ability to inhibit the IL-6Ra enhancement of IL-6 activity on M1 mouse myeloid leukemia cells. The ED50 for this effect is typically 0.6-3 µg/mL in the presence of 50 ng/mL recombinant human IL-6sR and 100 ng/mL recombinant human IL-6.

Mouse IL6ST / CD130 / gp130 Protein (Recombinant His,C-terminus)

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Expression System	Human Embryonic Kidney 293
Format:	Lyophilized

$300.00each

Catalog Number: LS-G51300-20

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Overview

Description: IL6ST / CD130 / gp130 Protein LS-G51300 is a Recombinant Mouse IL6ST / CD130 / gp130 produced in HEK 293 Cells Met1-Glu617 with His,C-terminus tag(s). It is biologically active and is low in endotoxin; Less than 1.0 EU/µg protein (determined by LAL method). For Research Use Only
Category: Proteins & Peptides > Proteins > Recombinant Proteins
Alternative Names: CD130 | CD130 antigen | IL-6R subunit beta | IL-6 receptor subunit beta | Membrane glycoprotein gp130 | Membrane glycoprotein 130 | IL-6RB | IL6ST | CDW130 | gp130 | IL-6R-beta
Origin Species: Mouse
NCBI GenBank: NM_002184
SwissProt: P40189

Protein

Expression System: Human Embryonic Kidney 293
Fusion Tag: Hexahistidine Tag
Molecular Weight: The secreted recombinant mouse gp130 consists of 606 amino acids and has a predicted molecular mass of 68 kDa. As a result of glycosylation, the apparent molecular mass of rm gp130 is approximately 80-90 kDa in SDS-PAGE under reducing conditions.
Protein Type: Recombinant
Amino Acid Sequence

Format

Purity: >97%
Conjugate/Label: Unconjugated
Endotoxin Level: < 1.0 EU/µg
Format: Lyophilized
Formulation: Lyophilized from sterile PBS, pH 7.4, with 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Purity Measurement Method: SDS-PAGE (Coomassie Stain)