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Human IL6ST / CD130 / gp130 Protein (Recombinant His-Fc)

Human IL6ST / CD130 / gp130 Protein (Recombinant His-Fc)

Expression SystemOther
Format:Lyophilized
See all IL6ST antibodies →
$526.00each
Catalog Number: LS-G97615-20

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Overview

Description
The recombinant human IL6ST/Fc is a disulfide-linked homodimer after removal of the signal peptide. The reduced monomer consists of 844 amino acids and has a predicted molecular mass of 96 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rh IL6ST/Fc monomer is approximately 125-140 kDa due to glycosylation. A DNA sequence encoding the extracellular domain (Met 1-Ile 618) of human IL6ST (NP_002175.2) precursor was fused with the C-terminal polyhistidine-tagged Fc region of human IgG1 at the C-terminus.
Category
Proteins & Peptides > Proteins > Recombinant Proteins
Alternative Names
CD130 | CD130 antigen | IL-6R subunit beta | IL-6 receptor subunit beta | Membrane glycoprotein gp130 | Membrane glycoprotein 130 | IL-6RB | IL6ST | CDW130 | gp130 | IL-6R-beta
Origin Species
Human
NCBI GenBank
NM_002184
SwissProt
P40189

Protein

Expression System
Other
Fusion Tag
Hexahistidine Tag, Human IgG1 Fc Tag
Molecular Weight
96 kDa
Protein Type
Recombinant
Amino Acid Sequence
1Met 1-Ile 618

13 aa

Format

Purity
>95%
Conjugate/Label
Unconjugated
Endotoxin Level
< 1.0 EU/µg
Format
Lyophilized
Formulation
Lyophilized from sterile PBS, pH 7.4
Purity Measurement Method
SDS-PAGE (Coomassie Stain)

Storage & Handling

Storage Conditions
Store at -70°C.

Request SDS/MSDS

To request an SDS/MSDS form for this product, please contact our Technical Support department at: technical@vectorlabs.com.