LSBio
Mouse FLT3LG / Flt3 Ligand Protein (Recombinant His, C-Terminal)

Mouse FLT3LG / Flt3 Ligand Protein (Recombinant His, C-Terminal)

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Expression SystemChinese Hamster Ovary
Format:Lyophilized
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$311.00each
Catalog Number: LS-G27262-10

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Overview

Description
Flt3L, also known as Fms-related tyrosine kinase 3 ligand and SL cytokine, is a single-pass type I membrane protein. It is expressed by stromal cells and T cells. Flt3L signals through tyrosine kinase receptor Flt3/Flk2 to stimulate the proliferation of early hematopoietic progenitor cells. It synergizes with other growth factors, such as GM-CSF, IL-3 and CSF, to promote the differentiation of both myeloid and lymphoid cells. Alternative splicing and proteolytic cleavage of membrane-bound Flt3L generates a soluble extracellular domain (ECD) isoform with full biological activity.
Category
Proteins & Peptides > Proteins > Recombinant Proteins
Alternative Names
FL | Flt3 ligand | FLT3LG | FLT3L | SL cytokine
Origin Species
Mouse
NCBI GenBank
NM_001459|NP_001450.2
SwissProt
P49771

Protein

Expression System
Chinese Hamster Ovary
Fusion Tag
Hexahistidine Tag
Molecular Weight
24-30 kDa (SDS-PAGE)
Protein Type
Recombinant
Amino Acid Sequence
1GTPDCYFSHS PISSNFKVKF RELTDHLLKD YPVTVAVNLQ DEKHCKALWS LFLAQRWIEQ
61LKTVAGSKMQ TLLEDVNTEI HFVTSCTFQP LPECLRFVQT NISHLLKDTC TQLLALKPCI
121GKACQNFSRC LEVQCQPDSS TLLPPRSPIA LEATELPEPR PRHHHHHH

168 aa

Format

Purity
>95%
Conjugate/Label
Unconjugated
Endotoxin Level
< 0.2 EU/µg
Format
Lyophilized
Formulation
Lyophilized from PBS
Purity Measurement Method
SDS-PAGE (Coomassie Stain)

Storage & Handling

Storage Conditions
Stable at -80°c for up to 6 months. Upon reconstitution, store at 4°c for up to 1 week or at -20°c for up to 2 months.

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