LSBio
Mouse FGF7 / KGF Protein (Recombinant)

Mouse FGF7 / KGF Protein (Recombinant)

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Expression SystemEscherichia coli (Prokaryotic)
Format:Lyophilized
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$302.00each
Catalog Number: LS-G27214-10

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Overview

Description
Keratinocyte Growth Factor (KGF) is a highly specific epithelial mitogen produced by fibroblasts and mesenchymal stem cells. KGF belongs to the heparin binding Fibroblast Growth Factor (FGF) family, and is known as FGF-7. However, in contrast to FGF-1, which binds to all known FGF receptors with high affinity, KGF only binds to a splice variant of the FGF receptor, FGFR2-IIIb. FGFR2-IIIb is expressedby most epithelial cells, indicating KGF's roleas a paracrine mediator. KGF induces the differentiation and proliferation of various epithelial cells such as keratinocytes in the epidermis, hair follicles and sebaceous glands. KGF is also responsible for wound repair of various tissuesincluding lung, bladder, and kidney. Recombinant mouse Keratinocyte Growth Factor (rmKGF) produced in E. coli is a single non-glycosylated polypeptide chain containing 163 amino acids. A fully biologically active molecule, rmKGF has a molecular mass of 18.7 kDa analyzed by reducing SDS-PAGE and is obtained by chromatographic techniques.
Category
Proteins & Peptides > Proteins > Recombinant Proteins
Alternative Names
FGF-7 | Fibroblast growth factor- 7 | Keratinocyte growth factor | FGF7 | Fibroblast growth factor 7 | HBGF-7 | KGF
Origin Species
Mouse
NCBI GenBank
NM_002009|NP_002000.1
SwissProt
P21781

Protein

Expression System
Escherichia coli (Prokaryotic)
Molecular Weight
18.7 kDa (SDS-PAGE)
Protein Type
Recombinant
Amino Acid Sequence
1CNDMSPEQTA TSVNCSSPER HTRSYDYMEG GDIRVRRLFC RTQWYLRIDK RGKVKGTQEM
61KNSYNIMEIR TVAVGIVAIK GVESEYYLAM NKEGKLYAKK ECNEDCNFKE LILENHYNTY
121ASAKWTHSGG EMFVALNQKG IPVKGKKTKK EQKTAHFLPM AIT

163 aa

Format

Purity
>95%
Conjugate/Label
Unconjugated
Endotoxin Level
< 0.2 EU/µg
Format
Lyophilized
Formulation
Lyophilized from PBS
Purity Measurement Method
SDS-PAGE (Coomassie Stain)

Storage & Handling

Storage Conditions
Stable at -80°c for up to 6 months. Upon reconstitution, store at 4°c for up to 2 weeks or at -20°c for up to 3 months.

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To request an SDS/MSDS form for this product, please contact our Technical Support department at: technical@vectorlabs.com.