LSBio
Human TROP2 / TACSTD2 Protein (Recombinant Fc, C-terminus)

Human TROP2 / TACSTD2 Protein (Recombinant Fc, C-terminus)

ProteinLSBio Guarantee
Expression SystemOther
Format:Lyophilized
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$268.00each
Catalog Number: LS-G137867-10

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Overview

Description
Tumor associated calcium signal transducer 2 (TACSTD2, TROP-2) is a type I cell surface glycoprotein that is highly expressed on human carcinomas. It was originally identified as an antigen present on human gastrointestinal tumors and is the second of two members of this family. Human and mouse TROP-2 share 87% amino acid (aa) similarity. TROP-2 is capable of transducing an intracellular calcium signal and may play a role in tumor growth. It also has adhesive functions.
Category
Proteins & Peptides > Proteins > Recombinant Proteins
Alternative Names
EGP-1 | EGP1 | GA7331 | M1S1 | TROP2 | Epithelial glycoprotein-1 | GA733-1 | gp50 | TACSTD2
Origin Species
Human
NCBI GenBank
NM_002353
SwissProt
P09758

Protein

Expression System
Other
Fusion Tag
Human IgG1 Fc Tag
Protein Type
Recombinant
Amino Acid Sequence
1TLVRPSEHAL VDNDGLYDPD CDPEGRFKAR QCNQTSVCWC VNSVGVRRTD KGDLSLRCDE
61LVRTHHILID LRHRPTAGAF NHSDLDAELR RLFRERYRLH PKFVAAVHYE QPTIQIELRQ
121NTSQKAAGDV DIGDAAYYFE RDIKGESLFQ GRGGLDLRVR GEPLQVERTL IYYLDEIPPK
181FSMKRLTVDD IEGRMDEPKS CDKTHTCPPC PAPELLGGPS VFLFPPKPKD TLMISRTPEV
241TCVVVDVSHE DPEVKFNWYV DGVEVHNAKT KPREEQYNST YRVVSVLTVL HQDWLNGKEY
301KCKVSNKALP APIEKTISKA KGQPREPQVY TLPPSREEMT KNQVSLTCLV KGFYPSDIAV
361EWESNGQPEN NYKTTPPVLD SDGSFFLYSK LTVDKSRWQQ GNVFSCSVMH EALHNHYTQK
421SLSLSPGK

428 aa

Format

Purity
>95%
Conjugate/Label
Unconjugated
Endotoxin Level
< 1 EU/µg
Format
Lyophilized
Formulation
Lyophilized from a sterile solution in PBS, pH 7.4.
Purity Measurement Method
SDS-PAGE (Coomassie Stain)

Storage & Handling

Storage Conditions
Before reconstitution: short term; store at room temperature for up to 3 weeks, long term; store at -20°C. After Reconstitution: short term; store at 4°C to 7°C for up to 7 days, long term; Aliquot and store at -20°C for up to 3 months. Avoid freeze-thaw cycles.

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