LSBio
Human TROP2 / TACSTD2 Protein (Recombinant 6His, C-terminus)

Human TROP2 / TACSTD2 Protein (Recombinant 6His, C-terminus)

ProteinLSBio Guarantee
Expression SystemOther
Format:Lyophilized
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$253.00each
Catalog Number: LS-G137875-10

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Overview

Description
Tumor associated calcium signal transducer 2 (TACSTD2, TROP-2) is a type I cell surface glycoprotein that is highly expressed on human carcinomas. It was originally identified as an antigen present on human gastrointestinal tumors and is the second of two members of this family. Human and mouse TROP-2 share 87% amino acid (aa) similarity. TROP-2 is capable of transducing an intracellular calcium signal and may play a role in tumor growth. It also has adhesive functions.
Category
Proteins & Peptides > Proteins > Recombinant Proteins
Alternative Names
EGP-1 | EGP1 | GA7331 | M1S1 | TROP2 | Epithelial glycoprotein-1 | GA733-1 | gp50 | TACSTD2
Origin Species
Human
NCBI GenBank
NM_002353
SwissProt
P09758

Protein

Expression System
Other
Fusion Tag
Hexahistidine Tag
Protein Type
Recombinant
Amino Acid Sequence
1aa88-274|T LVRPSEHALV DNDGLYDPDC DPEGRFKARQ CNQTSVCWCV NSVGVRRTDK
61GDLSLRCDEL VRTHHILIDL RHRPTAGAFN HSDLDAELRR LFRERYRLHP KFVAAVHYEQ
121PTIQIELRQN TSQKAAGDVD IGDAAYYFER DIKGESLFQG RGGLDLRVRG EPLQVERTLI
181YYLDEIPPKF SMKRLTVDHH HHHH

204 aa

Format

Purity
>95%
Conjugate/Label
Unconjugated
Endotoxin Level
< 1 EU/µg
Format
Lyophilized
Formulation
Lyophilized from a 0.2µm filtered concentrated solution in 1×PBS, pH7.4 containing 5% Trehalose 2mM EDTA
Purity Measurement Method
SDS-PAGE (Coomassie Stain)

Storage & Handling

Storage Conditions
Before reconstitution: short term; store at room temperature for up to 3 weeks, long term; store at -20°C. After Reconstitution: short term; store at 4°C to 7°C for up to 7 days, long term; Aliquot and store at -20°C for up to 3 months. Avoid freeze-thaw cycles.

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