TNFSF12 / TWEAK Antibody
Catalog Number: LS-C132767-100
100 µL / $702.00
Antibody: Rabbit Polyclonal
Applications: Western Blot
Reactivity: Human
Format: Liquid
Human TNFSF12 / TWEAK Protein (Recombinant)
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| Expression System | Chinese Hamster Ovary |
| Format: | Lyophilized |
$279.00each
Catalog Number: LS-G27201-10
Catalog Number: LS-G27201
For bulk orders or custom formulations:
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- Description
- TWEAK, short for TNF-related weak inducer of apoptosis, is also known as TNFSF12 and DR3LG. It is a type II transmembrane protein belonging to the TNF superfamily. It is expressed widely in many tissues, such as the heart, skeletal muscle, spleen and peripheral blood. Binding of TWEAK to its receptor TWEAKR induces NF-kappaB activation, chemokine secretion and apoptosis in certain cell types. TWEAK has also been reported to promote endothelial cell proliferation and migration, thus serving as a regulator of angiogenesis.
- Category
- Proteins & Peptides > Proteins > Recombinant Proteins
- Alternative Names
- APO3/DR3 ligand | APO3L | DR3LG | TNFSF12 | APO3 ligand | TWEAK
- Origin Species
- Human
- NCBI GenBank
- NM_003809|NP_003800.1
- SwissProt
- O43508
Protein
- Expression System
- Chinese Hamster Ovary
- Molecular Weight
- 20-22 kDa (SDS-PAGE)
- Protein Type
- Recombinant
- Amino Acid Sequence
1RKTRARRAIA AHYEVHPRPG QDGAQAGVDG TVSGWEEARI NSSSPLRYNR QIGEFIVTRA61GLYYLYCQVH FDEGKAVYLK LDLLVDGVLA LRCLEEFSAT AASSLGPQLR LCQVSGLLAL121RPGSSLRIRT LPWAHLKAAP FLTYFGLFQV H
151 aa
Format
- Purity
- >95%
- Conjugate/Label
- Unconjugated
- Endotoxin Level
- < 0.2 EU/µg
- Format
- Lyophilized
- Formulation
- Lyophilized from PBS
- Purity Measurement Method
- SDS-PAGE (Coomassie Stain)
Storage & Handling
- Storage Conditions
- Stable at -70°c for up to 6 months. Upon reconstitution, store at 4°c for up to 1 week or at -20°c for up to 2 months.
