LSBio
Human Soluble Interleukin 4 Receptor Alpha (sIL4Ra) Protein (Recombinant)

Human Soluble Interleukin 4 Receptor Alpha (sIL4Ra) Protein (Recombinant)

ProteinLSBio Guarantee
Expression SystemChinese Hamster Ovary
Format:Lyophilized
$274.00each
Catalog Number: LS-G133798-5

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Overview

Description
IL-4 can signal through type I and type II receptor complexes, which share a common gamma chain (?c). The type I receptor contains, in addition to the ?c, an IL-4Ra subunit, whereas the type II receptor contains the IL-13Ra. The secreted extracellular domain of IL-4Ra, called sIL-4Ra, binds IL-4 and antagonizes its activity. It plays an important role in regulating the differentiation of naive CD4+ T cells and class switching to IgG1 and IgE. PeproTech's CHO cell-derived Recombinant Human sIL-4 Receptor a is a 23.9 kDa glycoprotein corresponding to 209 amino acid residues of the extracellular domain of IL-4Ra. As a result of glycosylation, Recombinant Human sIL-4 Receptor a migrates with an apparent molecular mass of approximately 50-65 kDa by SDS-PAGE gel, under reducing conditions.
Category
Proteins & Peptides > Proteins > Recombinant Proteins
Origin Species
Human

Protein

Expression System
Chinese Hamster Ovary
Molecular Weight
23.9 kDa or 50-65 kDa
Protein Type
Recombinant
Amino Acid Sequence
1GNMKVLQEPT CVSDYMSIST CEWKMNGPTN CSTELRLLYQ LVFLLSEAHT CIPENNGGAG
61CVCHLLMDDV VSADNYTLDL WAGQQLLWKG SFKPSEHVKP RAPGNLTVHT NVSDTLLLTW
121SNPYPPDNYL YNHLTYAVNI WSENDPADFR IYNVTYLEPS LRIAASTLKS GISYRARVRA
181WAQCYNTTWS EWSPSTKWHN SYREPFEQH

209 aa

Format

Purity
>95%
Conjugate/Label
Unconjugated
Endotoxin Level
Not Tested
Format
Lyophilized
Formulation
Lyophilized
Purity Measurement Method
SDS-PAGE (Coomassie Stain)

Storage & Handling

Storage Conditions
Store at -20°C. Protect from moisture.

Request SDS/MSDS

To request an SDS/MSDS form for this product, please contact our Technical Support department at: technical@vectorlabs.com.