SMAD2
Catalog Number: LS-C100546-400
400 µL / $401.00
Antibody: Rabbit Polyclonal
Applications: Flow Cytometry, Immunofluorescence, Immunohistochemistry (general), Western Blot
Reactivity: Human, Mouse
Format: Liquid
Human SMAD2 Protein (Recombinant His)
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| Expression System | Escherichia coli (Prokaryotic) |
| Format: | Liquid |
$282.00each
Catalog Number: LS-G535-20
Catalog Number: LS-G535
For bulk orders or custom formulations:
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- Description
- SMAD2(Mothers against decapentaplegic homolog 2) belongs to the SMAD family of proteins that mediate signal transduction by the TGF-beta/activin/BMP-2/4 cytokine superfamily from receptor Ser/Thr protein kinases at the cell surface to the nucleus. Phosphorylated Smad2 is then able to form a complex with Smad4 or SARA. These complexes accumulate in the cell nucleus, where they are directly participating in the regulation of gene expression. Recombinant SMAD2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
- Category
- Proteins & Peptides > Proteins > Recombinant Proteins
- Alternative Names
- HMAD-2 | HSMAD2 | JV18-1 | Mad protein homolog smad2 | MADR2 | MADH2 | SMAD 2 | MAD homolog 2 | Mad-related protein 2 | SMAD2 | JV18 | Mother against DPP homolog 2 | Mothers against DPP homolog 2 | Sma- and Mad-related protein 2 | SMAD family member 2
- Origin Species
- Hu
- NCBI GenBank
- NM_005901, NP_005892.1
- SwissProt
- Q15796
Protein
- Expression System
- E.coli
- Fusion Tag
- 6×His
- Protein Type
- Recombinant
- Amino Acid Sequence
11-467aa|MG SSHHHHHHSS GLVPRGSHMS SILPFTPPVV KRLLGWKKSA GGSGGAGGGE61QNGQEEKWCE KAVKSLVKKL KKTGRLDELE KAITTQNCNT KCVTIPSTCS EIWGLSTPNT121IDQWDTTGLY SFSEQTRSLD GRLQVSHRKG LPHVIYCRLW RWPDLHSHHE LKAIENCEYA181FNLKKDEVCV NPYHYQRVET PVLPPVLVPR HTEILTELPP LDDYTHSIPE NTNFPAGIEP241QSNYIPETPP PGYISEDGET SDQQLNQSMD TGSPAELSPT TLSPVNHSLD LQPVTYSEPA301FWCSIAYYEL NQRVGETFHA SQPSLTVDGF TDPSNSERFC LGLLSNVNRN ATVEMTRRHI361GRGVRLYYIG GEVFAECLSD SAIFVQSPNC NQRYGWHPAT VCKIPPGCNL KIFNNQEFAA421LLAQSVNQGF EAVYQLTRMC TIRMSFVKGW GAEYRRQTVT STPCWIELHL NGPLQWLDKV481LTQMGSPSVR CSSMS
495 aa
Format
- Purity
- >95%
- Conjugate/Label
- Unconj
- Endotoxin Level
- Not Tested
- Format
- Liquid
- Formulation
- 20 mM Tris-HCl, pH 8.0, 0.1 M NaCl, 20% Glycerol
- Concentration
- 0.5 mg/mL
- Purity Measurement Method
- SDS-PAGE
Storage & Handling
- Storage Conditions
- Short term: store at 2°C to 8°C for up to 1 week. Long term: aliquot and store at -20°C to -80°C. Avoid freeze-thaw cycles.
