NPTX1
Catalog Number: LS-C100842-400
400 µL / $401.00
Antibody: Rabbit Polyclonal
Applications: Immunohistochemistry (general), Immunohistochemistry, Paraffin, Western Blot
Reactivity: Human
Format: Liquid
Human NPTX1 Protein (Recombinant 6His, C-terminus)
ProteinLSBio Guarantee
| Expression System | Other |
| Format: | Lyophilized |
$283.00each
Catalog Number: LS-G137889-10
Catalog Number: LS-G137889
For bulk orders or custom formulations:
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- Description
- Neuronal Pentraxin (NPTX1, NP1) is a secreted glycoprotein within the Pentraxin family. NPTX1 is co-expressed and forms heteromultimers with the related secreted protein, NPTX2/NARP, NPTXR (Neuronal Pentraxin Receptor) at excitatory synapses. Mature human NPTX1 shares 97% aa sequence identity with mouse, and rat NPTX1. It is produced by hippocampal, cerebral and cerebellar neurons, retinal ganglia and the inner nuclear layer of the retina. It is enriched on presynaptic axonal membranes where it forms complexes with NPTXR. It may be involved in mediating uptake of synaptic material during synapse remodeling or in mediating the synaptic clustering of AMPA glutamate receptors at a subset of excitatory synapses.
- Category
- Proteins & Peptides > Proteins > Recombinant Proteins
- Alternative Names
- Neuronal pentraxin-1 | NPTX1 | Neuronal pentraxin I | NP-I | NP1
- Origin Species
- Hu
- NCBI GenBank
- NM_002522
- SwissProt
- Q15818
Protein
- Expression System
- Other
- Fusion Tag
- 6×His
- Protein Type
- Recombinant
- Amino Acid Sequence
1QDFGPTRFIC TSVPVDADMC AASVAAGGAE ELRSSVLQLR ETVLQQKETI LSQKETIREL61TAKLGRCESQ STLDPGAGEA RAGGGRKQPG SGKNTMGDLS RTPAAETLSQ LGQTLQSLKT121RLENLEQYSR LNSSSQTNSL KDLLQSKIDE LERQVLSRVN TLEEGKGGPR NDTEERVKIE181TALTSLHQRI SELEKGQKDN RPGDKFQLTF PLRTNYMYAK VKKSLPEMYA FTVCMWLKSS241ATPGVGTPFS YAVPGQANEL VLIEWGNNPM EILINDKVAK LPFVINDGKW HHICVTWTTR301DGVWEAYQDG TQGGSGENLA PYHPIKPQGV LVLGQEQDTL GGGFDATQAF VGELAHFNIW361DRKLTPGEVY NLATCSTKAL SGNVIAWAES HIEIYGGATK WTFEACRQIN HHHHHH
416 aa
Format
- Purity
- >95%
- Conjugate/Label
- Unconj
- Endotoxin Level
- < 1 EU/µg
- Format
- Lyophilized
- Formulation
- Lyophilized from a sterile solution in PBS, pH 7.4, 1 mM EDTA
- Purity Measurement Method
- SDS-PAGE
Storage & Handling
- Storage Conditions
- Before reconstitution: short term; store at room temperature for up to 3 weeks, long term; store at -20°C. After Reconstitution: short term; store at 4°C to 7°C for up to 7 days, long term; Aliquot and store at -20°C for up to 3 months. Avoid freeze-thaw cycles.
