LIN28A / LIN28 Antibody
Catalog Number: LS-C203674-400
400 µL / $401.00
Antibody: Rabbit Polyclonal
Applications: Flow Cytometry, Western Blot
Reactivity: Human, Mouse
Format: Liquid
Human LIN28A / LIN28 Protein (Recombinant His)
ProteinLSBio Guarantee
| Expression System | Escherichia coli (Prokaryotic) |
| Format: | Liquid |
$282.00each
Catalog Number: LS-G637-10
Catalog Number: LS-G637
For bulk orders or custom formulations:
Request a QuoteOverview
- Description
- Lin-28 acts as a 'translational enhancer', driving specific mRNAs to polysomes and thus increasing the efficiency of protein synthesis. It is marker of undifferentiated human embryonic stem cells and has been used to enhance the efficiency of the formation of induced pluripotent stem (iPS) cells from human fibroblasts. It has also been shown to bind to the let-7 pre-miRNA and block production of the mature let-7 microRNA in mouse embryonic stem cells. Recombinant Lin28 protein was expressed in E.coli and purified by using conventional chromatography techniques.
- Category
- Proteins & Peptides > Proteins > Recombinant Proteins
- Alternative Names
- CSDD1 | Lin-28 homolog (C. elegans) | LIN-28 | Lin-28A | LIN28 | LIN28A | Protein lin-28 homolog A | Lin-28 homolog A (C. elegans) | ZCCHC1 | RNA-binding protein LIN-28
- Origin Species
- Human
- NCBI GenBank
- NM_024674|NP_078950.1
- SwissProt
- Q9H9Z2
Protein
- Expression System
- Escherichia coli (Prokaryotic)
- Fusion Tag
- Hexahistidine Tag
- Protein Type
- Recombinant
- Amino Acid Sequence
142-209aa|M GSSHHHHHHS SGLVPRGSHR SMGICKWFNV RMGFGFLSMT ARAGVALDPP61VDVFVHQSKL HMEGFRSLKE GEAVEFTFKK SAKGLESIRV TGPGGVFCIG SERRPKGKSM121QKRRSKGDRC YNCGGLDHHA KECKLPPQPK KCHFCQSISH MVASCPLKAQ QGPSAQGKPT181YFREEEEEIH SPTLLPEAQN
200 aa
Format
- Purity
- >90%
- Conjugate/Label
- Unconjugated
- Endotoxin Level
- Not Tested
- Format
- Liquid
- Formulation
- 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 0.1M NaCl, 0.1mM PMSF.
- Purity Measurement Method
- SDS-PAGE (Coomassie Stain)
Storage & Handling
- Storage Conditions
- Short term: store at 2°C to 8°C for up to 1 week. Long term: aliquot and store at -20°C to -80°C. Avoid freeze-thaw cycles.
