IL4R / CD124 Antibody
Catalog Number: LS-C487636-100
100 µL / $309.00
Antibody: Rabbit Polyclonal
Applications: Enzyme-Linked Immunosorbent Assay
Reactivity: Mouse
Format: Liquid
Human IL4R / CD124 Protein (Recombinant)
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| Expression System | Human Embryonic Kidney 293 |
| Format: | Lyophilized |
$311.00each
Catalog Number: LS-G27210-10
Catalog Number: LS-G27210
For bulk orders or custom formulations:
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- Description
- Interleukin-4 Receptor, also known as IL-4RA and CD124, is a transmembrane glycoprotein belonging to the class I receptor family. It is highly expressed by activated T-cells. IL-4RA couples with gamma chain to form the type I receptor for IL-4. The extracellular domain of IL-4RA binds to IL-4 and antagonizes its activity. IL-4RA plays an important role in Th2 cell differentiation, Ig class switching and alternative macrophage activation. It has also been implicated in allergic inflammation, tumor progression and atherogenesis.
- Category
- Proteins & Peptides > Proteins > Recombinant Proteins
- Alternative Names
- CD124 | CD124 antigen | IL-4RA | IL4R nirs variant 1 | IL4RA | IL4R | Interleukin 4 receptor | IL-4 receptor subunit alpha | IL-4R subunit alpha | IL-4R-alpha
- Origin Species
- Human
- NCBI GenBank
- NM_000418|NP_000409.1
- SwissProt
- P24394
Protein
- Expression System
- Human Embryonic Kidney 293
- Molecular Weight
- 40-45 kDa (SDS-PAGE)
- Protein Type
- Recombinant
- Amino Acid Sequence
1GNMKVLQEPT CVSDYMSIST CEWKMNGPTN CSTELRLLYQ LVFLLSEAHT CIPENNGGAG61CVCHLLMDDV VSADNYTLDL WAGQQLLWKG SFKPSEHVKP RAPGNLTVHT NVSDTLLLTW121SNPYPPDNYL YNHLTYAVNI WSENDPADFR IYNVTYLEPS LRIAASTLKS GISYRARVRA181WAQCYNTTWS EWSPSTKWHN SYREPFEQH
209 aa
Format
- Purity
- >95%
- Conjugate/Label
- Unconjugated
- Endotoxin Level
- < 0.2 EU/µg
- Format
- Lyophilized
- Formulation
- Lyophilized from PBS
- Purity Measurement Method
- SDS-PAGE (Coomassie Stain)
Storage & Handling
- Storage Conditions
- Stable at -80°c for up to 6 months. Upon reconstitution, store at 4°c for up to 1 week or at -20°c for up to 2 months.
