LSBio
Human FASLG / Fas Ligand Protein (Recombinant Human IgG1 Fc)

Oligomerization of FasL (h) efficiently triggers Jurkat cell death.Method: Jurkat cells were treated O/N with the indicated concentrations of MegaFasL, Soluble (human) (rec.) (rec.) (rec.) or FasL, Soluble (human) (rec.) + TNF ligands enhancer (2 fold-dilutions, first concentration of 1000ng/ml). Cell death was quantified using PMS/MTS. The oligomeric FasL recombinant proteins (MegaFasL, Soluble (human), Fc:FasL, Soluble (human) and FasL, Soluble (human) + TNF ligands enhancer) kill Jurkat cells at IC50 <0.2ng/ml.

Human FASLG / Fas Ligand Protein (Recombinant Human IgG1 Fc)

Expression SystemHuman Embryonic Kidney 293
Format:Lyophilized
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$416.00each
Catalog Number: LS-G3966-10

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Overview

Description
Human FasL (aa 139-281) is fused at the N-terminus to the Fc portion of human IgG1.
Category
Proteins & Peptides > Proteins > Recombinant Proteins
Alternative Names
ALPS1B | Apoptosis antigen ligand | APTL | CD95L | CD95 ligand | CD178 antigen | CD95-L | Fas antigen ligand | Fas ligand | FASL | TNFSF6 | APT1LG1 | CD178 | FASLG
Origin Species
Hu
SwissProt
P48023

Protein

Expression System
HEK293
Fusion Tag
hFc
Molecular Weight
~50kDa (SDS-PAGE)
Protein Type
Recombinant
Amino Acid Sequence
1aa 139-281

10 aa

Format

Purity
>95%
Conjugate/Label
Unconj
Endotoxin Level
< 0.01 EU/µg
Format
Lyophilized
Formulation
Lyophilized from PBS
Purity Measurement Method
SDS-PAGE

Storage & Handling

Storage Conditions
Store lyophilized at -20°C for up to 6 months. Once reconstituted store at 4°C for immediate use.

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To request an SDS/MSDS form for this product, please contact our Technical Support department at: technical@vectorlabs.com.