Endostatin Antibody
Catalog Number: LS-C128727-100
100 µg / $576.00
Antibody: Mouse Monoclonal
Applications: Enzyme-Linked Immunosorbent Assay
Reactivity: Human
Format: Liquid
Human Endostatin Protein (Recombinant)
ProteinLSBio Guarantee
| Expression System | Yeast |
| Format: | Lyophilized |
$311.00each
Catalog Number: LS-G27307-100
Catalog Number: LS-G27307
For bulk orders or custom formulations:
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- Description
- Endostatin is a cleaved product of the carboxyl-terminal domain of collagen XVIII. It functions as an anti-angiogenic cytokine that is expressed in various organs especially with high levels in liver, lung, and kidney. Endostatin inhibits angiogenesis by blocking the pro-angiogenic activities of VEGF and FGF-basic. Recombinant Endostatin expressed in yeast, whichcauses G1 arrest of endothelial cells. Endostatin treatment results in apoptosis of HUVE and HMVE cells. Recombinant human Endostatin is a 20.2 kDa protein consisting of 184 amino acid residues.
- Category
- Proteins & Peptides > Proteins > Recombinant Proteins
- Alternative Names
- COL18A1 | Collagen | type XVIII | alpha 1 | Collagen alpha-1(XVIII) chain | Endostatin | KNO | KNO1 | KS | Multi-functional protein MFP | Antiangiogenic agent | Collagen alpha 1(xviii) | Knobloch syndrome | type 1
- Origin Species
- Human
- NCBI GenBank
- NM_030582|NP_085059.2
- SwissProt
- P39060
Protein
- Expression System
- Yeast
- Protein Type
- Recombinant
- Amino Acid Sequence
1AHSHRDFQPV LHLVALNSPL SGGMRGIRGA DFQCFQQARA VGLAGTFRAF LSSRLQDLYS61IVRRADRAAV PIVNLKDELL FPSWEALFSG SEGPLKPGAR IFSFDGKDVL RHPTWPQKSV121WHGSDPNGRR LTESYCETWR TEAPSATGQA SSLLGGRLLG QSAASCHHAY IVLCIENSFM181TASK
184 aa
Format
- Purity
- >97%
- Conjugate/Label
- Unconjugated
- Endotoxin Level
- Not Tested
- Format
- Lyophilized
- Formulation
- Lyophilized with 17 mM citric-phosphate buffer, pH 6.2.
- Purity Measurement Method
- SDS-PAGE (Coomassie Stain)
Storage & Handling
- Storage Conditions
- Store Lyophilized at room temperature up to 1 month; Reconstituted for up to 2 weeks at 2°C to 8°C. Aliquot and freeze at -20°C for long term storage. Avoid freeze/thaw cycles.
