LSBio
Human CDON / Cdo Protein (Recombinant 6His, C-terminus)

Human CDON / Cdo Protein (Recombinant 6His, C-terminus)

ProteinLSBio Guarantee
Expression SystemOther
Format:Lyophilized
See all CDON antibodies →
$275.00each
Catalog Number: LS-G137897-10

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Overview

Description
CDO (CAMrelated/down-regulated by oncogenes) is a member of the Immunoglubulin (Ig) superfamily, Ig/Fibronectin (FN) type III repeat family of cell surface proteins. Human CDO is a type I transmembrane (TM) glycoprotein. It is synthesized as a 1287 amino acid (aa) precursor that contains a 25 aa signal sequence, a 938 aa extracellular domain (ECD), a 21 aa TM segment and a 303 aa cytoplasmic region. The ECD contains five C2-type Iglike domains, followed by three FN type III repeats. The ECD of human CDO is 85% aa identical to mouse CDO ECD. CDO is found on muscle precursor and neural progenitor cells of the embryo. It likely promotes muscle differentiation, and contributes to axon guidance and neuronal patterning.
Category
Proteins & Peptides > Proteins > Recombinant Proteins
Alternative Names
CDON | HPE11 | ORCAM | CDO | Cdon homolog (mouse) | CDON1
Origin Species
Human
NCBI GenBank
NM_016952
SwissProt
Q4KMG0

Protein

Expression System
Other
Fusion Tag
Hexahistidine Tag
Protein Type
Recombinant
Amino Acid Sequence
1DLAPYFTSEP LSAVQKLGGP VVLHCSAQPV TTRISWLHNG KTLDGNLEHI KIHQGTLTIL
61SLNSSLLGYY QCLANNSIGA IVSGPATVSV AVLGDFGSST KHVITAEEKS AGFIGCRVPE
121SNPKAEVRYK IRGKWLKHST ENYLILPSGN LQILNVSLED KGSYKCAAYN PVTHQLKVEP
181IGRKLLVSRP SSDDVHILHP THSQALAVLS RSPVTLECVV SGVPAPQVYW LKDGQDIAPG
241SNWRRLYSHL ATDSVDPADS GNYSCMAGNK SGDVKYVTYM VNVLEHASIS KGLQDQIVSL
301GATVHFTCDV HGNPAPNCTW FHNAQPIHPS ARHLTAGNGL KISGVTVEDV GMYQCVADNG
361IGFMHSTGRL EIENDGGFKP VIITAPVSAK VADGDFVTLS CNASGLPVPV IRWYDSHGLI
421TSHPSQVLRS KSRKSQLSRP EGLNLEPVYF VLSQAGASSL HIQAVTQEHA GKYICEAANE
481HGTTQAEASL MVVPFETNTK AETVTLPDAA QNDDRSKRDG SETGLLSSFP VKVHPSAVES
541APEKNASGIS VPDAPIILSP PQTHTPDTYN LVWRAGKDGG LPINAYFVKY RKLDDGVGML
601GSWHTVRVPG SENELHLAEL EPSSLYEVLM VARSAAGEGQ PAMLTFRTSK EKTASSKNTQ
661ASSPPVGIPK YPVVSEAANN NFGVVLTDSS RHSGVPEAPD RPTISTASET SVYVTWIPRA
721NGGSPITAFK VEYKRMRTSN WLVAAEDIPP SKLSVEVRSL EPGSTYKFRV IAINHYGESF
781RSSASRPYQV VGFPNRFSSR PITGPHIAYT EAVSDTQIML KWTYIPSSNN NTPIQGFYIY
841YRPTDSDNDS DYKRDVVEGS KQWHMIGHLQ PETSYDIKMQ CFNEGGESEF SNVMICETKV
901KRVPGASEYP VKDLSTPPHH HHHH

924 aa

Format

Purity
>95%
Conjugate/Label
Unconjugated
Endotoxin Level
< 1 EU/µg
Format
Lyophilized
Formulation
Lyophilized from a sterile solution in PBS, pH 7.4.
Purity Measurement Method
SDS-PAGE (Coomassie Stain)

Storage & Handling

Storage Conditions
Before reconstitution: short term; store at room temperature for up to 3 weeks, long term; store at -20°C. After Reconstitution: short term; store at 4°C to 7°C for up to 7 days, long term; Aliquot and store at -20°C for up to 3 months. Avoid freeze-thaw cycles.

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