Human Apolipoprotein H Antibody (IgG) ELISA Kit (Sandwich ELISA)
Catalog Number: LS-F67372-1
1 plate / $591.00
Reactivity: Human
Detection Method Colorimetric
Format: 96-Well Strip Plate
TRPV4 Antibody (aa100-150)
Primary AntibodyLSBio Guarantee
| Antibody: | Rabbit Polyclonal |
| Applications: | Immunofluorescence, Immunohistochemistry (general), Immunohistochemistry, Paraffin, Western Blot |
| Reactivity: | Mouse, Rat |
| Format: | Lyophilized |
$235.00each
Catalog Number: LS-C94498-100
Catalog Number: LS-C94498
For bulk orders or custom formulations:
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- Description
- TRPV4 antibody LS-C94498 is an unconjugated rabbit polyclonal antibody to TRPV4 (aa100-150) from mouse. It is reactive with mouse and rat. Validated for IF, IHC and WB. Cited in 11 publications.
- Application
- IF, IHC, IHC-P, WB
- Reactivity
- Ms, Rt
- Intended Use
- Research Use Only
- Guarantees
- This antibody carries the LSBio 100% Guarantee. ✓
- Category
- Antibodies > Primary Antibodies > Polyclonal Antibodies
- Alternative Names
- CMT2C | HMSN2C | OTRPC4 | SSQTL1 | VR-OAC | VRL-2 | TRPV4 | Osm-9-like TRP channel 4 | SPSMA | TRP12 | VRL2 | VROAC | SMAL
- UniProt Number
- Q9HBA0
- NCBI GenBank
- NM_021625 | NP_067638.3
- SwissProt
- Q9HBA0
Target
- Target
- Mouse TRPV4
- Antigen Species
- Mouse
- Epitope
- aa100-150 of mouse, rat TRPV4
- Gene Name
- TRPV4
Antibody
- Host Species
- Rabbit
- Clonality
- Polyclonal
- Origin Species
- Human
Immunogen
- Immunogen
- Synthetic peptide from 1t cytoplasmic domain of mouse TRPV4 conjugated to an immunogenic carrier protein.
- Immunogen Type
- Synthetic Peptide (Linear)
Format
- Conjugate/Label
- Unconjugated
- Format
- Lyophilized
- Formulation
- Lyophilized
- Volume
- 100 Microliter
- Preservative
- No
- Purification Method
- Unpurified (Serum / Ascites / Supernatant)
Storage & Handling
- Storage Conditions
- Maintain lyophilized and reconstituted antibodies at -20°C for long term storage and at 2°C to 8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze/thaw cycles.
The polymodal ion channel transient receptor potential vanilloid 4 modulates calcium flux, spiking rate, and apoptosis of mouse retinal ganglion cells. Ryskamp DA, Witkovsky P, Barabas P, Huang W, Koehler C, Akimov NP, Lee SH, Chauhan S, Xing W, Rentera RC, Liedtke W, Krizaj D. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2011;31:7089-101.
PubMed: 21562271 · PMC: PMC3109951
Neurite outgrowth and synaptophysin expression of postnatal CNS neurons on GaP nanowire arrays in long-term retinal cell culture. Piret G, Perez MT, Prinz CN. Biomaterials. 2013;34:875-87.
PubMed: 23131535
Dual contribution of TRPV4 antagonism in the regulatory effect of vasoinhibins on blood-retinal barrier permeability: diabetic milieu makes a difference. Arredondo Zamarripa D, Noguez Imm R, Bautista Cortés AM, Vázquez Ruíz O, Bernardini M, Fiorio Pla A, Gkika D, Prevarskaya N, López-Casillas F, Liedtke W, Clapp C, Thébault S. Scientific reports. 2017;7:13094.
PubMed: 29026201 · PMC: PMC5638810
Polarity of varicosity initiation in central neuron mechanosensation. Gu Y, Jukkola P, Wang Q, Esparza T, Zhao Y, Brody D, Gu C,. The Journal of cell biology. 2017;216:2179-2199.
PubMed: 28606925
TRPV4 Does Not Regulate the Distal Retinal Light Response. Yarishkin O, Phuong TTT, Lakk M, Križaj D. Advances in experimental medicine and biology. 2018;1074:553-560.
PubMed: 29721987 · PMC: PMC6414060
The expression and function of TRPV4 channels in primate retinal ganglion cells and bipolar cells. Gao F, Yang Z, Jacoby RA, Wu SM, Pang JJ. Cell death & disease. 2019 May;10:364.
PubMed: 31064977 · PMC: PMC6504919
Immunocytochemical Profiling of Cultured Mouse Primary Retinal Cells. Marina C Zalis, Sebastian Johansson, Ulrica Englund-Johansson. The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society. 2017 Apr;65:223-239.
PubMed: 28151698 · PMC: PMC5407564
Mechanisms underlying selective coupling of endothelial Ca 2+<sup> signals with eNOS vs. IK/SK channels in systemic and pulmonary arteries. Matteo Ottolini , Zdravka Daneva, Yen-Lin Chen, Eric L Cope, Ramesh B Kasetti, Gulab S Zode, Swapnil K Sonkusare. The Journal of physiology. 2020 Sep;;598:3577-3596.
PubMed: 32463112 · PMC: PMC7484264
Generators of Pressure-Evoked Currents in Vertebrate Outer Retinal Neurons. Ji-Jie Pang, Fan Gao, Samuel M Wu. Cells. 2021 May;10:1288.
PubMed: 34067375 · PMC: PMC8224636
Endothelial pannexin 1-TRPV4 channel signaling lowers pulmonary arterial pressure in mice. Zdravka Daneva, Matteo Ottolini , Yen Lin Chen, Eliska Klimentova, Maniselvan Kuppusamy, Soham A Shah, Richard D Minshall, Cheikh I Seye, Victor E Laubach, Brant E Isakson, Swapnil K Sonkusare. eLife. 2021 Sep;10:e67777.
PubMed: 34490843 · PMC: PMC8448527
Lysophosphatidic acid as a CSF lipid in posthemorrhagic hydrocephalus that drives CSF accumulation via TRPV4-induced hyperactivation of NKCC1. Trine L Toft-Bertelsen, Dagne Barbuskaite, Eva Kjer Heerfordt, Sara Diana Lolansen, Søren Norge Andreassen, Nina Rostgaard, Markus Harboe Olsen, Nicolas H Norager, Tenna Capion, Martin Fredensborg Rath, Marianne Juhler, Nanna MacAulay. Fluids and barriers of the CNS. 2022 September;19:69.
PubMed: 36068581 · PMC: PMC9450297
