TP73 / p73 Antibody (N-Terminus, clone 5B429, Azide-free)
Primary AntibodyLSBio Guarantee
| Antibody: | Mouse Monoclonal |
| Applications: | Chromatin Immunoprecipitation, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (general), Immunohistochemistry, Frozen, Immunohistochemistry, Paraffin, Immunoprecipitation, Western Blot |
| Reactivity: | Human, Mouse |
| Format: | Liquid |
$394.00each
Catalog Number: LS-C368321-0.1
Catalog Number: LS-C368321
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- Description
- P73 antibody LS-C368321 is an unconjugated mouse monoclonal antibody to p73 (TP73) (N-Terminus) from human. It is reactive with human and mouse. Validated for ChrIP, ICC, IF, IHC, IP and WB.
- Application
- ChIP, ICC, IF, IHC, IHC-F, IHC-P, IP, WB
- Reactivity
- Hu, Ms
- Intended Use
- Research Use Only
- Guarantees
- This antibody carries the LSBio 100% Guarantee. ✓
- Category
- Antibodies > Primary Antibodies > Monoclonal Antibodies
- Alternative Names
- p53-like transcription factor | p73 | p53-related protein | Tumor protein p73 | TP73
- Recommended Dilution: IF/ICC
- 1:10 - 1:500|1:10 - 1:500
- Recommended Dilution: IP
- 1:10 - 1:500
- UniProt Number
- O15350
- NCBI GenBank
- NM_005427 | NP_005418.1
- SwissProt
- O15350
Target
- Target
- Human TP73 / p73
- Antigen Species
- Human
- Epitope
- Human TP73 / p73. P73 antibody (clone 5B429) recognizes all of the TAp73 isoforms i. e. isoforms with an intact NH2-terminal transactivation domain (Thottassery et el, 2006, PMID 16505115). Sayan et al 2005 (PMID 15781249) showed that p73 IMG-246/ NBP2-24737 reacted with all tested TAp73 isoforms but not deltaNp73 whereas p73 antibody clone 5B1288 (NB100-56674 / IMG-259A ) showed reactivity against all p73 isoforms including delta Np73. Caspase-cleaved p73 fragments, including 55 kD and 45 kD, have been described in literature (Sayan et al, 2008). p73 antibody clone 5B429 has also been referred to as 429 in the literature.
- Gene Name
- TP73
Antibody
- Host Species
- Mouse
- Clonality
- Monoclonal
- Clone
- 5B429
- Isotype
- IgG1
- Light Chain
- Kappa Light Chain
Immunogen
- Immunogen
- This antibody was raised against full-length human p73. It reacts with an epitope that is located on the N-Terminus of human p73. It does not cross react with p53.
Format
- Conjugate/Label
- Unconjugated
- Format
- Liquid
- Formulation
- PBS. No stabilizing proteins added.
- Preservative
- No
- Purification Method
- Protein G Affinity
Storage & Handling
- Storage Conditions
- Short term: store at 4°C. Long term: aliquot and store at -20°C. Avoid freeze-thaw cycles.
- Recommended Storage Buffer
- PBS