TP73 / p73 Antibody
Catalog Number: LS-C760193-100
100 µL / $477.00
Antibody: Rabbit Polyclonal
Applications: Western Blot
Reactivity: Human
Format: Liquid
Anti-p73 antibody IHC of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
IHC-plus™ TP73 / p73 Antibody (N-Terminus, clone 5B429)
Primary AntibodyLSBio Guarantee
| Antibody: | Mouse Monoclonal |
| Applications: | Immunocytochemistry, Immunohistochemistry (general), Immunohistochemistry, Paraffin, Immunoprecipitation, Western Blot |
| Reactivity: | Human, Mouse |
| Format: | Liquid |
$383.00each
Catalog Number: LS-B2086-50
Catalog Number: LS-B2086
For bulk orders or custom formulations:
Request a QuoteOverview
- Description
- P73 antibody LS-B2086 is an unconjugated mouse monoclonal antibody to p73 (TP73) (N-Terminus) from human. It is reactive with human and mouse. Validated for ICC, IHC, IP and WB. Tested on 20 paraffin-embedded human tissues.
- Application
- ICC, IHC, IHC-P, IP, WB
- Reactivity
- Hu, Ms
- Intended Use
- Research Use Only
- Guarantees
- This product carries the LSBio 100% Guarantee. ✓
- Category
- Antibodies > Primary Antibodies > Monoclonal Antibodies
- Alternative Names
- p53-like transcription factor | p73 | p53-related protein | Tumor protein p73 | TP73
- Recommended Dilution: IHC-P
- 5 µg/ml
- Recommended Dilution: WB
- 2 µg/ml
- UniProt Number
- O15350
- NCBI GenBank
- NM_005427 | NP_005418.1
- SwissProt
- O15350
Target
- Target
- TP73 / p73
- Antigen Species
- Human
- Specificity
- Full-length human p73. It reacts with an epitope that is located on the N-terminal region of human p73. It does not cross react with p53.
- Epitope
- Recognizes all of the TAp73 isoforms i. e. isoforms with an intact NH2-terminal transactivation domain (Thottassery et el, 2006, PMID 16505115). Sayan et al 2005 (PMID 15781249) showed that p73 IMG-246/ NBP2-24737 reacted with all tested TAp73 isoforms but not deltaNp73 whereas p73 antibody clone 5B1288 (NB100-56674 / IMG-259A ) showed reactivity against all p73 isoforms including delta Np73. Caspase-cleaved p73 fragments, including 55 kD and 45 kD, have been described in literature (Sayan et al, 2008). p73 antibody clone 5B429 has also been referred to as 429 in the literature.
- Gene Name
- TP73
Antibody
- Host Species
- Mouse
- Clonality
- Monoclonal
- Clone
- 5B429
- Origin Species
- Human
Immunogen
- Immunogen
- Full-length human p73. It reacts with an epitope that is located on the N-Terminus of human p73. It does not cross react with p53.
- Immunogen Type
- Full-Length Recombinant Protein
Format
- Conjugate/Label
- Unconjugated
- Format
- Liquid
- Formulation
- PBS, 0.05% Sodium Azide
- Concentration
- 1 mg/mL
- Animal Free
- No
- Carrier-Free
- Yes
- Preservative
- Yes
- Purification Method
- Protein G Affinity
Storage & Handling
- Storage Conditions
- Short term: store at 4°C. Long term: aliquot and store at -20°C. Avoid freeze-thaw cycles.
- Recommended Storage Buffer
- PBS
